Multifocal Ewing sarcoma of the foot

Multifocal skeletal Ewing sarcoma is very rare. A 10-year-old boy presented with multiple independent lesions involving the first phalanx of the middle toe, the second metatarsal bone, the cuneiform and cuboid bones, and the talus. Diagnosis of Ewing sarcoma was confirmed by open biopsy of 2 nonadjacent bones. Chest computed tomography disclosed the presence of multiple lung metastases. The patient underwent chemotherapy, below-knee amputation, and lung irradiation. To the best of the authors' knowledge, no similar case has been previously reported in the literature.