Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity

被引：17

作者：

Nguyen-Ba, P ^{[1
]}

Turcotte, N ^{[1
]}

Yuen, L ^{[1
]}

Bédard, J ^{[1
]}

Quimpère, M ^{[1
]}

Chan, L ^{[1
]}

机构：

[1] BioChem Therapeut Inc, Laval, PQ H7V 4A7, Canada

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(98)00649-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

We have recently described the discovery of new leads in the area of anti-HCMV research. Further structure - activity relationship studies have allowed us to identify potent and selective anti-HCMV nucleotide analogs. The synthesis as well as structure - activity relationship studies are described. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3561 / 3566

页数：6

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