Fatal Exophiala infections in China, with a report of seven cases

被引:63
作者
Li, D. -M. [1 ,2 ,3 ]
Li, R. -Y. [2 ,4 ]
de Hoog, G. S. [2 ,3 ]
Sudhadham, M. [3 ]
Wang, D. -L. [2 ]
机构
[1] Peking Univ Third Hosp, Dept Dermatol, Beijing, Peoples R China
[2] Peking Univ, Res Ctr Med Mycol, Beijing 100871, Peoples R China
[3] Cent Bur Schimmelcultures, Utrecht, Netherlands
[4] Peking Univ First Hosp, Dept Dermatol, Beijing 100034, Peoples R China
基金
中国国家自然科学基金;
关键词
Black yeast; mycosis; neurotropism; Exophiala; rDNA; WANGIELLA-DERMATITIDIS; CEREBRAL PHEOHYPHOMYCOSIS; UNITED-STATES; JEANSELMEI; SPINIFERA; ENDOPHTHALMITIS; RAMICHLORIDIUM; ABSCESS; FUNGI;
D O I
10.1111/j.1439-0507.2010.01859.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
During the past four decades, seven patients were documented in China to have died from Exophiala infections. Causative agents were Exophiala dermatitidis, Exophiala spinifera, Exophiala jeanselmei and a new Exophiala species, Exophiala asiatica. We retrospectively analysed the clinical characteristics of these infections in China and confirmed the identity of aetiological agents of Chinese fatal cases using rDNA ITS sequence analysis. While E. dermatitidis displayed neurotropism, E. spinifera showed osteotropism. The other two species, E. jeanselmei and E. asiatica had caused brain infections in China.
引用
收藏
页码:E136 / E142
页数:7
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