Prevalence of recommended anticoagulation by guidelines preadmission and its impact on the incidence of acute myocardial infarction (AMI) and in-hospital outcomes after AMI in atrial fibrillation patients

被引：7

作者：

Bai, Ying ^{[1
]}

Liu, Xin-Yao ^{[1
]}

Liu, Yue ^{[2
]}

Guo, Shi-Dong ^{[3
]}

Wang, Zhen-Zhou ^{[4
]}

Shi, Xu-Bo ^{[1
]}

Jin, Yuanyuan ^{[2
]}

Zhong, Peng ^{[5
]}

机构：

[1] Capital Med Univ, Beijing Tongren Hosp, Cardiovasc Ctr, 1 Dong Jiao Min Xiang St, Beijing 100730, Peoples R China

[2] Harbin Med Univ, Dept Cardiol, Affiliated Hosp 1, Harbin, Heilongjiang, Peoples R China

[3] China Japan Friendship Hosp, Emergency Dept, 2 YinghuaDongjie, Beijing 100029, Peoples R China

[4] Peking Univ Peoples Hosp, Trauma Ctr, Beijing 100044, Peoples R China

[5] Capital Med Univ, Beijing Friendship Hosp, Dept Ultrasound, Beijing 100050, Peoples R China

来源：

JOURNAL OF THROMBOSIS AND THROMBOLYSIS | 2022年 / 54卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Atrial fibrillation; Recommended coagulation; Acute myocardial infarction; All-cause death; PERCUTANEOUS CORONARY INTERVENTION; 2011 ACCF/AHA/SCAI GUIDELINE; ORAL ANTICOAGULATION; CHINESE PATIENTS; FOCUSED UPDATE; WARFARIN; STROKE; DABIGATRAN; THERAPY; MANAGEMENT;

D O I：

10.1007/s11239-021-02622-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study was designed to explore the prevalence of recommended anticoagulation by guidelines before admission and its impact on the incidence of acute myocardial infarction (AMI) and the AMI associated in-hospital outcomes in patients with atrial fibrillation (AF). 10,725 patients with AF at their first hospitalizations in our hospitals were retrospectively reviewed, with a prevalence of recommended anticoagulation preadmission 24.41% (Number = 2618). They had lower risk of AMI incidence (Adjusted OR 0.66, 95%CI 0.54-0.81, p < 0.001) compared to those without recommended anticoagulation after multivariate logistic regression. Furthermore, recommended anticoagulation preadmission reduced in-hospital all-cause death associated with AMI in univariate logistic analysis, but had no impact on the risk of in-hospital bleeding and stroke after AMI both in univariate and multivariate logistic analysis. The prevalence of recommended anticoagulation before admission was 24.41% in China. Recommended anticoagulation reduced incidence of hospitalized AMI, but had no impact on the associated in-hospital bleeding and stroke risk after AMI.

引用

页码：91 / 96

页数：6

共 22 条

[1] Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-regression analysis [J].

Bai, Ying ;

Guo, Shi-Dong ;

Deng, Hai ;

Shantsila, Alena ;

Fauchier, Laurent ;

Ma, Chang-Sheng ;

Lip, Gregory Y. H. .

AGE AND AGEING, 2018, 47 (01) :9-17

[2] The Global Burden of Atrial Fibrillation and Stroke A Systematic Review of the Clinical Epidemiology of Atrial Fibrillation in Asia [J].

Bai, Ying ;

Wang, Yan-Liang ;

Shantsila, Alena ;

Lip, Gregory Y. H. .

CHEST, 2017, 152 (04) :810-820

[3] How long should dual antiplatelet therapy be applied after covered stent implantation? A case report on clinical implications of left anterior descending artery aneurysm treatment with covered stent implantation [J].

Hrycek, Eugeniusz ;

Zurek, Przemyslaw ;

Walawska-Hrycek, Anna ;

Nowakowski, Przemyslaw ;

Zurakowski, Aleksander .

KARDIOLOGIA POLSKA, 2023, 81 (11) :1155-1156

[4] CHA2DS2-VASc Recalibration With an Additional Age Category (50-64 Years) Enhances Stroke Risk Stratification in Chinese Patients With Atrial Fibrillation [J].

Chan, Pak-Hei ;

Lau, Chu-Pak ;

Tse, Hung-Fat ;

Chiang, Chern-En ;

Siu, Chung-Wah .

CANADIAN JOURNAL OF CARDIOLOGY, 2016, 32 (12) :1381-1387

[5] Current Status and Time Trends of Oral Anticoagulation Use Among Chinese Patients With Nonvalvular Atrial Fibrillation The Chinese Atrial Fibrillation Registry Study [J].

Chang, San-Shuai ;

Dong, Jian-Zeng ;

Ma, Chang-Sheng ;

Du, Xin ;

Wu, Jia-Hui ;

Tang, Ri-Bo ;

Xia, Shi-Jun ;

Guo, Xue-Yuan ;

Yu, Rong-Hui ;

Long, De-Yong ;

Bai, Rong ;

Liu, Nian ;

Sang, Cai-Hua ;

Jiang, Chen-Xi ;

Liu, Xiao-Hui ;

Pan, Jian-Hong ;

Lip, Gregory Y. H. .

STROKE, 2016, 47 (07) :1803-1810

[6] Apixaban in Patients with Atrial Fibrillation [J].

Connolly, Stuart J. ;

Eikelboom, John ;

Joyner, Campbell ;

Diener, Hans-Christoph ;

Hart, Robert ;

Golitsyn, Sergey ;

Flaker, Greg ;

Avezum, Alvaro ;

Hohnloser, Stefan H. ;

Diaz, Rafael ;

Talajic, Mario ;

Zhu, Jun ;

Pais, Prem ;

Budaj, Andrzej ;

Parkhomenko, Alexander ;

Jansky, Petr ;

Commerford, Patrick ;

Tan, Ru San ;

Sim, Kui-Hian ;

Lewis, Basil S. ;

Van Mieghem, Walter ;

Lip, Gregory Y. H. ;

Kim, Jae Hyung ;

Lanas-Zanetti, Fernando ;

Gonzalez-Hermosillo, Antonio ;

Dans, Antonio L. ;

Munawar, Muhammad ;

O'Donnell, Martin ;

Lawrence, John ;

Lewis, Gayle ;

Afzal, Rizwan ;

Yusuf, Salim .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 364 (09) :806-817

[7] Dabigatran versus Warfarin in Patients with Atrial Fibrillation. [J].

Connolly, Stuart J. ;

Ezekowitz, Michael D. ;

Yusuf, Salim ;

Eikelboom, John ;

Oldgren, Jonas ;

Parekh, Amit ;

Pogue, Janice ;

Reilly, Paul A. ;

Themeles, Ellison ;

Varrone, Jeanne ;

Wang, Susan ;

Alings, Marco ;

Xavier, Denis ;

Zhu, Jun ;

Diaz, Rafael ;

Lewis, Basil S. ;

Darius, Harald ;

Diener, Hans-Christoph ;

Joyner, Campbell D. ;

Wallentin, Lars .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (12) :1139-1151

[8] Cardiovascular, Bleeding, and Mortality Risks in Elderly Medicare Patients Treated With Dabigatran or Warfarin for Nonvalvular Atrial Fibrillation [J].

Graham, David J. ;

Reichman, Marsha E. ;

Wernecke, Michael ;

Zhang, Rongmei ;

Southworth, Mary Ross ;

Levenson, Mark ;

Sheu, Ting-Chang ;

Mott, Katrina ;

Goulding, Margie R. ;

Houstoun, Monika ;

MaCurdy, Thomas E. ;

Worrall, Chris ;

Kelman, Jeffrey A. .

CIRCULATION, 2015, 131 (02) :157-164

[9] Apixaban versus Warfarin in Patients with Atrial Fibrillation [J].

Granger, Christopher B. ;

Alexander, John H. ;

McMurray, John J. V. ;

Lopes, Renato D. ;

Hylek, Elaine M. ;

Hanna, Michael ;

Al-Khalidi, Hussein R. ;

Ansell, Jack ;

Atar, Dan ;

Avezum, Alvaro ;

Cecilia Bahit, M. ;

Diaz, Rafael ;

Easton, J. Donald ;

Ezekowitz, Justin A. ;

Flaker, Greg ;

Garcia, David ;

Geraldes, Margarida ;

Gersh, Bernard J. ;

Golitsyn, Sergey ;

Goto, Shinya ;

Hermosillo, Antonio G. ;

Hohnloser, Stefan H. ;

Horowitz, John ;

Mohan, Puneet ;

Jansky, Petr ;

Lewis, Basil S. ;

Luis Lopez-Sendon, Jose ;

Pais, Prem ;

Parkhomenko, Alexander ;

Verheugt, Freek W. A. ;

Zhu, Jun ;

Wallentin, Lars .

NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (11) :981-992

[10] Usefulness of Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Myocardial Infarction [J].

Guimaraes, Patricia O. ;

Zakroysky, Pearl ;

Goyal, Abhinav ;

Lopes, Renato D. ;

Kaltenbach, Lisa A. ;

Wang, Tracy Y. .

AMERICAN JOURNAL OF CARDIOLOGY, 2019, 123 (01) :12-18

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