A case of 5-fluorouracil-induced peripheral neuropathy

被引:10
|
作者
Werbrouck, Bart F. [1 ]
Pauwels, Walter J. [2 ]
De Bleecker, Jan L. [1 ,3 ]
机构
[1] Ghent Univ Hosp, Dept Neurol, B-9000 Ghent, Belgium
[2] St Lucas Gen Hosp, Dept Gastroenterol, Ghent, Belgium
[3] St Lucas Gen Hosp, Dept Neurol, Ghent, Belgium
关键词
A waves; chemotherapy; 5-fluorouracil; peripheral neuropathy; rectal neoplasm;
D O I
10.1080/15563650701438763
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
The standard adjuvant therapy for rectal cancer is 5-fluorouracil (5-FU) often combined with radiotherapy. Well-documented side effects of 5-FU include nausea, vomiting and diarrhoea, leukopenia and thrombocytopenia, hand-foot syndrome, mucositis, and cardiotoxicity. Peripheral neurotoxicity has only rarely been reported. We report a patient with a stage II rectal carcinoma who developed a mild axonal sensorimotor neuropathy at the end of a 5-FU therapy.
引用
收藏
页码:264 / 266
页数:3
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