Influence of two salicylate components on the particle size of an oil-in-water emulsion with nonionic surfactants

被引:1
作者
Mestres, G [1 ]
Nielloud, F [1 ]
Fortune, R [1 ]
Devoisselle, JM [1 ]
Marti, R [1 ]
Maillols, H [1 ]
机构
[1] UNIV MONTPELLIER 1, FAC SCI ECON, LAB ECONOMET, F-34060 MONTPELLIER, FRANCE
关键词
bootstrap methods; light scattering; methyl salicylate; oil-in-water emulsion; particle size analysis; sodium salicylate;
D O I
10.3109/03639049609063237
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This paper reports a study undertaken using techniques of static and dynamic light scattering to investigate the influence of sodium salicylate and methyl salicylate on droplet size of oil-in-water emulsions. The rates of changes were measured by determining the size and distribution of the oil droplet in the material. All emulsions showed a bimodal size distribution; the mean diameters and polydispersity were calculated from intensity. These data were analyzed with nonlinear regressions and bootstrap methodology. An amount of methyl salicylate component induced a decrease of mean diameter and standard deviation. On the contrary, sodium salicylate entailed the growth of all droplet populations and coalescence for the highest concentration.
引用
收藏
页码:1193 / 1199
页数:7
相关论文
共 20 条
[1]  
[Anonymous], REGRESSION NONLINEAI
[2]  
BELLOCQ AM, 1987, MICROEMULSIONS STRUC
[3]  
Berne BJ, 1990, DYNAMIC LIGHT SCATTE
[4]  
BERTERO M, 1994, EXPONENTIAL SAMPLING, V1
[5]  
BEZOT C, 1986, ANAL FONCTIONS CORRE
[6]   FAST AND ACCURATE APPROXIMATE DOUBLE BOOTSTRAP CONFIDENCE-INTERVALS [J].
DICICCIO, TJ ;
MARTIN, MA ;
YOUNG, GA .
BIOMETRIKA, 1992, 79 (02) :285-295
[7]  
FARINATO RS, 1983, ENCY EMULSION TECHNO, V1
[8]   BOOTSTRAPPING REGRESSION-MODELS [J].
FREEDMAN, DA .
ANNALS OF STATISTICS, 1981, 9 (06) :1218-1228
[9]  
HUNTER RJ, 1992, INTRO MODERN COLLOID
[10]   USE OF RESAMPLING TECHNIQUES TO ESTIMATE THE VARIANCE OF PARAMETERS IN PHARMACOLOGICAL ASSAYS WHEN EXPERIMENTAL PROTOCOLS PRECLUDE INDEPENDENT REPLICATION - AN EXAMPLE USING SCHILD REGRESSIONS [J].
LUTZ, MW ;
KENAKIN, TP ;
CORSI, M ;
MENIUS, JA ;
KRISHNAMOORTHY, C ;
RIMELE, T ;
MORGAN, PH .
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 1995, 34 (01) :37-46