Multifunctional Eu-doped NaGd(MoO4)2 nanoparticles functionalized with poly(L-lysine) for optical and MRI imaging

被引：20

作者：

Laguna, Mariano ^{[1
]}

Nunez, Nuria O. ^{[1
]}

Rodriguez, Veronica ^{[1
]}

Cantelar, Eugenio ^{[2
]}

Stepien, Grazyna ^{[3
]}

Garcia, Maria Luisa ^{[4
]}

de la Fuente, Jesus M. ^{[5
]}

Ocana, Manuel ^{[1
]}

机构：

[1] CSIC, Inst Ciencia Mat Sevilla, Amer Vespucio 49, Seville 41092, Spain

[2] Univ Autonoma Madrid, Fac Ciencias, Dept Fis Mat, Francisco Tomas & Valiente 7, E-28049 Madrid, Spain

[3] Univ Zaragoza, Inst Nanociencia Aragon, Edificio I D,C Mariano Esquillor S-N, Zaragoza 50018, Spain

[4] Andalusian Ctr Nanomed & Biotechnol, BIONAND Parque Tecnol Andalucia, Malaga, Spain

[5] Univ Zaragoza, CSIC, Inst Ciencia Mat Aragon, Edificio I D,C Mariano Esquillor S-N, Zaragoza 50018, Spain

来源：

DALTON TRANSACTIONS | 2016年 / 45卷 / 41期

关键词：

MAGNETIC-RESONANCE; HYDROTHERMAL SYNTHESIS; MEDIATED SYNTHESIS; ENERGY-TRANSFER; CONTRAST AGENT; NANOCRYSTALS; LUMINESCENCE; DELIVERY; OXIDE; PHOTOLUMINESCENCE;

D O I：

10.1039/c6dt02663j

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A method for the synthesis of non-aggregated and highly uniform Eu3+ doped NaGd(MoO4)(2) nanoparticles is reported for the first time. The obtained particles present tetragonal structure, ellipsoidal shape and their size can be varied by adjusting the experimental synthesis parameters. These nanoparticles, which were coated with citrate anions and functionalised with PLL, have also been developed in order to improve their colloidal stability in physiological medium (2-(N-morpholino) ethanesulfonic acid, MES). A study of the luminescent dynamics of the samples as a function of the Eu doping level has been conducted in order to find the optimum nanophosphors, whose magnetic relaxivity and cell viability have also been evaluated for the first time for this system, in order to assess their suitability as multifunctional probes for optical (in vitro) and magnetic bioimaging applications.

引用

页码：16354 / 16365

页数：12

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