Two new cyclopentenone metabolites from Streptomyces sp. HU119

被引：0
|
作者：
Song, Wen-Shuai [1 ]
Qi, Huan [2 ]
Zhang, Shao-Yong [2 ]
Wang, Han [1 ]
Zhang, Cheng-Hong [2 ]
Xiang, Wen-Sheng [1 ]
Wang, Ji-Dong [2 ]
Wang, Xiang-Jing [1 ]
机构：
[1] Northeast Agr Univ, Sch Life Sci, Life Sci & Biotechnol Res Ctr, Harbin 150030, Peoples R China
[2] Huzhou Univ, Coll Life Sci, Key Lab Vector Biol & Pathogen Control Zhejiang P, Huzhou 313000, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2022年 / 24卷 / 11期
关键词：
Cyclopentenone metabolites; Streptomyces sp; HU119; Tai Lake sediment; structure elucidation;
D O I：
10.1080/10286020.2021.2023505
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two previously undescribed cyclopentenone metabolites, (S)-2-(3-acetylamino-2-methyl)propyl-3-butyl-2-cyclopenten-1-one (1) and (S)-2-(3-acetylamino-2-ethyl)propyl-3-butyl-2-cyclopenten-1-one (2), were isolated from the fermentation broth of the strain Streptomyces sp. HU119. The structures of 1 and 2 were determined by the comprehensive spectroscopic analysis, including 1 D, 2 D NMR, MS spectral analysis and the comparison with data from the literature. The absolute configurations were elucidated by experimental and calculated optical rotations (OR). Compounds 1 and 2 displayed weak cytotoxic activity.
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收藏
页码：1058 / 1063
页数：6
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