Bacteriophage imaging: past, present and future

被引:12
作者
Almeida, Gabriel M. F. [1 ]
Leppanen, Miika [1 ,2 ]
Maasilta, Ilari J. [2 ]
Sundberg, Lotta-Riina [1 ]
机构
[1] Univ Jyvaskyla, Ctr Excellence Biol Interact, Dept Biol & Environm Sci, Nanosci Ctr, Survontie 9C, FI-40014 Jyvaskyla, Finland
[2] Univ Jyvaskyla, Dept Phys, Nanosci Ctr, Survontie 9C, FI-40014 Jyvaskyla, Finland
基金
芬兰科学院;
关键词
Bacteriophage; Phage; Virus; Imaging; Structure; Microscopy; X-RAY-DIFFRACTION; ELECTRON-MICROSCOPY; HUMAN ADENOVIRUS; RESOLUTION; VIRUSES; WATERS; EPIFLUORESCENCE; ABUNDANCE; PROTEIN; CELL;
D O I
10.1016/j.resmic.2018.05.006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The visualization of viral particles only became possible after the advent of the electron microscope. The first bacteriophage images were published in 1940 and were soon followed by many other publications that helped to elucidate the structure of the particles and their interaction with the bacterial hosts. As sample preparation improved and new technologies were developed, phage imaging became important approach to morphologically classify these viruses and helped to understand its importance in the biosphere. In this review we discuss the main milestones in phage imaging, how it affected our knowledge on these viruses and recent developments in the field. (C) 2018 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:488 / 494
页数:7
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