Gastric Neuroendocrine Carcinoma with Rapid Progression

被引：15

作者：

Iwamoto, Maho ^{[1
]}

Gotoda, Takuji ^{[1
]}

Noda, Yasuhiro ^{[1
]}

Esaki, Mitsuru ^{[1
]}

Moriyama, Mitsuhiko ^{[1
]}

Yoshida, Nao ^{[2
]}

Takayama, Tadatoshi ^{[2
]}

Kobayashi, Hiroko ^{[3
]}

Masuda, Shinobu ^{[3
]}

机构：

[1] Nihon Univ, Dept Internal Med, Div Gastroenterol & Hepatol, Sch Med, Tokyo, Japan

[2] Nihon Univ, Dept Digest Surg, Sch Med, Tokyo, Japan

[3] Nihon Univ, Dept Pathol, Sch Med, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 10期

关键词：

gastric neuroendocrine carcinoma; gastric cancer; MIXED ADENONEUROENDOCRINE CARCINOMA; STOMACH; TUMORS; EPIDEMIOLOGY; PATHOLOGY; CELL;

D O I：

10.2169/internalmedicine.3961-19

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

As gastric neuroendocrine carcinoma (NEC) is a rapidly growing cancer, most cases are diagnosed at advanced stages. We herein report a 74-year-old woman with an early-stage gastric NEC whose history included endoscopic submucosal dissection treatment for three early-stage gastric cancer lesions five years prior to the current presentation. We also describe the changes observed over time. An endoscopic examination during follow-up revealed an NEC (measuring 6 mm) in the gastric vestibule, for which distal gastrectomy was performed. Four months before surgery, the carcinoma exhibited specific morphological changes and lymphovascular invasion (despite the tumor being stage 1), suggesting a high-grade NEC.

引用

页码：1271 / 1276

页数：6

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