Although both esophageal and anorectal abnormalities predominate in systemic sclerosis, gastric involvement is less recognized, leading to complications, e.g., motor disorders responsible for dyspeptic manifestations and gastric bleeding related to watermelon stomach. In this prospective study, we observed a high prevalence of gastric electrical activity impairment, using cutaneous electrogastrography, in 11 patients with systemic sclerosis. Moreover, we failed to find a correlation between electrogastrographic dysfunction and both systemic sclerosis duration and subsets, severity of the nailfold capillaroscopic microangiopathy or esophageal motor impairment. We therefore suggest that these parameters should not be considered as predictive factors of gastric involvement in patients with systemic sclerosis.