Lung transplantation and rejection

被引：0
作者：
Wohlschlaeger, J. [1 ]
Sommerwerck, U. [2 ]
Jonigk, D. [3 ]
Rische, J. [3 ]
Baba, H. A. [1 ]
Mueller, K. M. [4 ]
机构：
[1] Univ Klinikum Essen, Inst Pathol & Neuropathol, D-45147 Essen, Germany
[2] Univ Klinikum Essen, W Deutsch Lungenzentrum, Abt Pulmol, Ruhrlandklin Essen, D-45147 Essen, Germany
[3] Hannover Med Sch, Inst Pathol, Hannover, Germany
[4] Univ Klin Munster, Gerhard Domagk Inst Pathol, Munster, Germany
来源：
PATHOLOGE | 2011年 / 32卷 / 02期
关键词：
Lung transplantation; Acute cellular rejection; Bronchiolitis obliterans syndrome; Histopathology; Lung biopsy;
D O I：
10.1007/s00292-010-1403-1
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Lung transplantation is the ultimate therapeutical approach for the treatment of both children and adults with terminal congenital or acquired lung disease. In contrast to survival rates during the first year following transplantation, the long-term survival for patients after lung transplantation has not significantly improved in the past. In addition to other complications, acute cellular rejection constitutes a major cause for diminished function of pulmonary grafts, and can, among other factors, be causative for chronic rejection (bronchiolitis obliterans syndrome, BOS). In 2006, the International Society for Heart and Lung Transplantation (ISHLT) provided a revised version of the grading system for acute and chronic rejection of pulmonary grafts.
引用
收藏
页码：104 / 112
页数：9
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