SARS-CoV-2 Neutralizing Antibodies in Chile after a Vaccination Campaign with Five Different Schemes

被引：4

作者：

Aguilera, Ximena ^{[1
]}

Hormazabal, Juan ^{[2
]}

Vial, Cecilia ^{[2
]}

Jimena Cortes, Lina ^{[2
]}

Gonzalez, Claudia ^{[1
]}

Rubilar, Paola ^{[1
]}

Apablaza, Mauricio ^{[3
]}

Ramirez-Santana, Muriel ^{[4
]}

Icaza, Gloria ^{[5
]}

Nunez-Franz, Loreto ^{[6
]}

Castillo-Laborde, Carla ^{[1
]}

Ramirez-Riffo, Carolina ^{[2
]}

Perez, Claudia ^{[7
]}

Quezada-Gate, Ruben ^{[4
]}

Said, Macarena ^{[6
]}

Vial, Pablo ^{[2
,8
]}

机构：

[1] Clin Alemana Univ Desarrollo, Ctr Epidemiol & Polit Salud, Fac Med, Av Plaza 680, Santiago 7610658, Chile

[2] Clin Alemana Univ Desarrollo, Inst Ciencias & Innovac Med, Fac Med, Av Plaza 680, Santiago 7610658, Chile

[3] Univ Desarrollo, Fac Gobierno, Av Plaza 680, Santiago 7610658, Chile

[4] Univ Catolica Norte, Fac Med, Publ Hlth Dept, Larrondo 1281, Coquimbo 1780000, Chile

[5] Univ Talca, Inst Matemat, Ave Uno Poniente 1141, Talca 3460000, Chile

[6] Univ Talca, Fac Ciencias Salud, Dept Salud Publ, Ave Uno Poniente 1141, Talca 3460000, Chile

[7] Clin Alemana Univ Desarrollo, Fac Med, Escuela Enfermeria, Av Plaza 680, Santiago 7610658, Chile

[8] Clin Alemana Santiago, Ave Vitacura 5951, Santiago 7650568, Chile

来源：

VACCINES | 2022年 / 10卷 / 07期

关键词：

neutralizing antibodies; vaccines; BNT162b2; CoronaVac; AZD1222; COVID-19; SARS-CoV-2; cross-sectional design; vaccine-preventable diseases; viruses; COVID-19; VACCINES; BNT162B2;

D O I：

10.3390/vaccines10071051

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Using levels of neutralizing antibodies (nAbs), we evaluate the successful Chilean SARS-CoV-2 vaccine campaign, which combines different vaccine technologies and heterologous boosters. From a population-based study performed in November 2021, we randomly selected 120 seropositive individuals, organized into six groups of positive samples (20 subjects each) according to natural infection history and the five most frequent vaccination schemes. We conclude that the booster dose, regardless of vaccine technology or natural infection, and mRNA vaccines significantly improve nAbs response.

引用

页数：7

共 50 条

[1] SARS-CoV-2 Neutralizing Antibodies in Mexican Population: A Five Vaccine Comparison
Alcorta-Nunez, Fernando
Perez-Ibave, Diana Cristina
Burciaga-Flores, Carlos Horacio
Garza, Miguel Angel
Gonzalez-Escamilla, Moises
Rodriguez-Nino, Patricia
Gonzalez-Guerrero, Juan Francisco
Alcorta-Garza, Adelina
Vidal-Gutierrez, Oscar
Ramirez-Correa, Genaro A.
Garza-Rodriguez, Maria Lourdes
DIAGNOSTICS, 2023, 13 (06)
[2] Placental Transfer Efficiency of Neutralizing Antibodies on SARS-CoV-2 Vaccination before and after Pregnancy in Mexican Women
Martinez-Quezada, Rebeca
Miguel-Rodriguez, Carlos Emilio
Ramirez-Lozada, Tito
Valencia-Ledezma, Omar Esteban
Acosta-Altamirano, Gustavo
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (03)
[3] Levels of Neutralizing Antibodies against SARS-CoV-2 in Mothers and Neonates after Vaccination during Pregnancy
da Silva Filho, Antonio Oliveira
Goncalves, Daniel Nazario
de Lima, Leticia Karina Ramos
Alves, Damocles Aurelio Nascimento da Silva
Falcao, Felipe Jose de Andrade
Falcao, Rosangela Estevao Alves
VACCINES, 2023, 11 (03)
[4] SARS-CoV-2 infection long time after full vaccination is related to a lack of neutralizing antibodies
Alidjinou, Enagnon Kazali
Gaillot, Olivier
Guigon, Aurelie
Tinez, Claire
Lazrek, Mouna
Bocket, Laurence
Engelmann, Ilka
Hober, Didier
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2022, 102 (01)
[5] Monitoring of SARS-CoV-2 Specific Antibodies after Vaccination
Guiomar, Raquel
Santos, Ana Joao
Melo, Aryse Martins
Costa, Ines
Matos, Rita
Rodrigues, Ana Paula
Kislaya, Irina
Silva, Anabela Santos
Roque, Carla
Nunes, Carla
Aguiar, Joaquim
Graca, Fatima
Silva Graca, Antonio
Machado, Ausenda
VACCINES, 2022, 10 (02)
[6] Previous Infection Combined with Vaccination Produces Neutralizing Antibodies with Potency against SARS-CoV-2 Variants
Ibarrondo, F. Javier
Hofmann, Christian
Ali, Ayub
Ayoub, Paul
Kohn, Donald B.
Yang, Otto O.
MBIO, 2021, 12 (06):
[7] SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies
Ng, Kevin W.
Faulkner, Nikhil
Finsterbusch, Katja
Wu, Mary
Harvey, Ruth
Hussain, Saira
Greco, Maria
Liu, Yafei
Kjaer, Svend
Swanton, Charles
Gandhi, Sonia
Beale, Rupert
Gamblin, Steve J.
Cherepanov, Peter
McCauley, John
Daniels, Rodney
Howell, Michael
Arase, Hisashi
Wack, Andreas
Bauer, David L., V
Kassiotis, George
SCIENCE TRANSLATIONAL MEDICINE, 2022, 14 (655)
[8] IgA quantification as a good predictor of the neutralizing antibodies levels after vaccination SARS-CoV-2
Fernandes-Siqueira, Lorena O.
Sousa, Bruna G.
Cleto, Carlos E.
Wermelinger, Luciana S.
Caetano, Beatriz L. L.
Pacheco, Agatha R.
Costa, Simone M.
Almeida, Fabio C. L.
Ferreira, Gustavo C.
Salmon, Didier
Alves, Ada M. B.
Da Poian, Andrea T.
JOURNAL OF CLINICAL VIROLOGY PLUS, 2022, 2 (04):
[9] Neutralizing antibodies for SARS-CoV-2 infection
Berenguer, Juan
REVISTA ESPANOLA DE QUIMIOTERAPIA, 2022, 35 : 16 - 19
[10] Applicability of probabilistic graphical models for early detection of SARS-CoV-2 reactive antibodies after SARS-CoV-2 vaccination in hematological patients
Luis Pinana, Jose
Rodriguez-Belenguer, Pablo
Caballero, Dolores
Martino, Rodrigo
Lopez-Corral, Lucia
Terol, Maria-Jose
Vazquez, Lourdes
Calabuig, Marisa
Sanz-Linares, Gabriela
Marin-Jimenez, Francisca
Alonso, Carmen
Montoro, Juan
Ferrer, Elena
Facal, Ana
Pascual, Maria-Jesus
Rodriguez-Fernandez, Alicia
Olave, Maria T.
Cascales-Hernandez, Almudena
Gago, Beatriz
Hernandez-Rivas, Jose-Angel
Villalon, Lucia
Corona, Magdalena
Roldan-Perez, Alicia
Ribes-Amoros, Julia
Gonzalez-Santillana, Clara
Garcia-Sanz, Ramon
Navarro, David
Serrano-Lopez, Antonio J.
Cedillo, Angel
Soria-Olivas, Emilio
Sureda, Anna
Solano, Carlos
ANNALS OF HEMATOLOGY, 2022, 101 (09) : 2053 - 2067

← 1 2 3 4 5 →