Quantitative CT for Volumetric Analysis of Medical Images: Initial Results for Liver Tumors

被引：3

作者：

Behnaz, Alexander S. ^{[1
]}

Snider, James ^{[1
]}

Eneh, Chibuzor ^{[1
]}

Esposito, Giuseppe ^{[1
]}

Wilson, Emmanuel ^{[1
]}

Yaniv, Ziv ^{[1
]}

Cohen, Emil ^{[1
]}

Cleary, Kevin ^{[1
]}

机构：

[1] Georgetown Univ, ISIS Ctr, Dept Radiol, Washington, DC 20057 USA

来源：

MEDICAL IMAGING 2010: IMAGE PROCESSING | 2010年 / 7623卷

关键词：

volumetric analysis; disease progression; computed tomography (CT); software; SEGMENTATION;

D O I：

10.1117/12.844344

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Quantitative CT for volumetric analysis of medical images is increasingly being proposed for monitoring patient response during chemotherapy trials. An integrated MATLAB GUI has been developed for an oncology trial at Georgetown University Hospital. This GUI allows for the calculation and visualization of the volume of a lesion. The GUI provides an estimate of the volume of the tumor using a semi-automatic segmentation technique. This software package features a fixed parameter adaptive filter from the ITK toolkit and a tumor segmentation algorithm to reduce inter-user variability and to facilitate rapid volume measurements. The system also displays a 3D rendering of the segmented tumor, allowing the end user to have not only a quantitative measure of the tumor volume, but a qualitative view as well. As an initial validation test, several clinical cases were hand-segmented, and then compared against the results from the tool, showing good agreement.

引用

页数：6

共 5 条

[1]

AVILA R, 2008, QUANTITATIVE IMAGING, P39

[2] MATLAB-ITK interface for medical image filtering, segmentation, and registration [J].

Chu, Vincent ;

Hamarneh, Ghassan .

MEDICAL IMAGING 2006: IMAGE PROCESSING, PTS 1-3, 2006, 6144

[3]

IBANEZ L, 2005, ITK SOFTWARE GUIDE, P193

[4] User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability [J].

Yushkevich, Paul A. ;

Piven, Joseph ;

Hazlett, Heather Cody ;

Smith, Rachel Gimpel ;

Ho, Sean ;

Gee, James C. ;

Gerig, Guido .

NEUROIMAGE, 2006, 31 (03) :1116-1128

[5]

ZHAO B, 2008, QUANTITATIVE IMAGING, P39

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