Bioimaging in the mid-infrared using an organometallic carbonyl tag

被引:56
作者
Kong, Kien Voon
Chew, Wee
Lim, Lina Hsiu Kim
Fan, Wai Yip
Leong, Weng Kee [1 ]
机构
[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore
[2] Inst Chem & Engn Sci, Singapore 627, Singapore
[3] Natl Univ Singapore, Dept Physiol, Singapore 117597, Singapore
关键词
D O I
10.1021/bc070133a
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Two stable and water-soluble organometallic carbonyl cluster derivatives have been prepared and shown to enter the cell with ease. The CO stretching vibrations afford strong mid-infrared signals which have been demonstrated, for the first time, to be of utility in cell imaging via an IR microscope.
引用
收藏
页码:1370 / 1374
页数:5
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