Controlling wound healing through debridement

被引：41

作者：

Jones, MA ^{[1
]}

Song, B ^{[1
]}

Thomas, DM ^{[1
]}

机构：

[1] Montclair State Univ, Dept Math Sci, Montclair, NJ 07043 USA

来源：

MATHEMATICAL AND COMPUTER MODELLING | 2004年 / 40卷 / 9-10期

关键词：

D O I：

10.1016/j.mcm.2003.09.041

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

The formation of slough (dead tissue) on a wound is widely accepted as an inhibitor to natural wound healing. In this article, a system of differential equations that models slough/wound interaction is developed. We prove a threshold theorem that provides conditions on the amount of slough to guarantee wound healing. As a state-dependent time scale, debridement (the periodic removal of slough) is used as a control. We show that closure of the wound can be reached in infinite time by debriding. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1057 / 1064

页数：8