Synthesis of Cyclopentachromans by N-Heterocyclic Carbene-Mediated Homoenolate Annulation of Chroman-3-ene-4-ones

被引：6

作者：

Krishnan, Jagadeesh ^{[1
,2
]}

Sinu, C. R. ^{[1
]}

Anusree, M. ^{[1
]}

Lakshmi, K. C. Seetha ^{[1
,3
]}

Mayadevi, T. S. ^{[1
]}

Eringathodi, Suresh ^{[4
]}

Nair, Vijay ^{[1
]}

机构：

[1] Natl Inst Interdisciplinary Sci & Technol, CSIR, Chem Sci & Technol Div, Trivandrum 695019, Kerala, India

[2] Acad Sci & Innovat Res, New Delhi 110001, India

[3] Mahatma Gandhi Univ, Sch Chem Sci, Kottayam 686560, Kerala, India

[4] CSMCRI, CSIR, Analyt Dept & Centralized Instrument Facil, Bhavnagar 364002, Gujarat, India

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 5卷 / 06期

关键词：

arylidene tetralones; chromanones; homoenolates; N-heterocyclic carbenes; thiochromanones; tricyclic pentenes; NHC-CATALYZED ANNULATION; BOND-FORMING REACTIONS; STEREOSELECTIVE-SYNTHESIS; DIASTEREOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; SPIRO-HETEROCYCLES; GAMMA-LACTAMS; ACYL AZOLIUMS; ENALS; CYCLOPENTENES;

D O I：

10.1002/ajoc.201600074

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An N-heterocyclic carbene (NHC)-mediated homoenolate reaction strategy for the efficient synthesis of a wide variety of tricyclic pentenes with potential biological activity is reported.

引用

页码：778 / 785

页数：8

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