Distribution and antifungal susceptibility of Candida clinical isolations coming from six health care centers in the metropolitan area of Caracas, Venezuela (years 2003-2005)

被引：10

作者：

Dolande Franco, Maribel E. ^{[1
]}

Reviakina, Vera ^{[1
]}

Mercedes Panizo, Maria ^{[1
]}

Macero, Carolina ^{[2
]}

Moren, Xiomara ^{[2
]}

Calvo, Alberto

Selgrad, Sofia ^{[1
]}

Papatzikos, Juana ^{[3
]}

Vergara, Vivian ^{[3
]}

Jose Mendoza, Maria

机构：

[1] Inst Nacl Higiene Rafael Rangel, Dept Micol, Caracas 1050, Venezuela

[2] Inst Med La Floresta, Microbiol Lab, Caracas, Venezuela

[3] Hosp Clin Caracas, Microbiol Lab, Caracas, Venezuela

来源：

REVISTA IBEROAMERICANA DE MICOLOGIA | 2008年 / 25卷 / 01期

关键词：

antifungals; candidiasis; epidemiology; invasive fungal infection; susceptibility;

D O I：

10.1016/S1130-1406(08)70005-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The aim of this study was to investigate the frequency and antifungal susceptibility of Candida clinical isolations coming from patients with candidiasis in six health care centers of Caracas, Venezuela metropolitan area. The laboratory reports were retrospectively revised from January 2003 through August 2005. The isolated yeasts identification was carried out by conventional methods and antifungal susceptibility was evaluated by ATB-fungus (bioMerieux, France) and Etest (AB Biodisk, Solna, Sweden). One thousand nine hundred seventy seven (1,977) yeasts were studied and their susceptibility testing were carried out only in 1,414 of them. C. albicans was the most isolated yeast (46.7%) and none-albicans Candida-species represented more than half of the isolations (53.4%). All the isolated yeasts evaluated presented CMls <1 mu g/ml to anfotericina B and showed variable susceptibility percentages to fluconazole (91.5%), itraconazole (80%) and voriconazole (98.6%).

引用

页码：17 / 21

页数：5

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