Study of photon migration with various source-detector separations in near-infrared spectroscopic brain imaging based on three-dimensional Monte Carlo modeling

被引:27
作者
Lee, CK
Sun, CW [2 ]
Lee, PL
Lee, HC
Yang, CC
Jiang, CP
Tong, YP
Yeh, TC
Hsieh, JC
机构
[1] Natl Taiwan Univ, Grad Inst Electroopt Engn, Taipei, Taiwan
[2] Ind Technol Res Inst, Ctr Biomed Engn, Hsinchu, Taiwan
[3] Natl Cent Univ, Dept Elect Engn, Tao Yuan, Taiwan
[4] Taipei Vet Gen Hosp, Integrated Brain Res Unit, Taipei, Taiwan
关键词
D O I
10.1364/OPEX.13.008339
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We have simulated the photon migration with various source-detector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed. (c) 2005 Optical Society of America.
引用
收藏
页码:8339 / 8348
页数:10
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