Zn(OAc)2•2H2O-catalyzed synthesis of a-aminophosphonates under neat reaction

被引：15

作者：

Arigala, Uma Ravi Sankar ^{[1
]}

Matcha, Chaitanya ^{[1
]}

Yoon, Kuk Ro ^{[1
]}

机构：

[1] Hannam Univ, Dept Chem, Coll Life Sci & Nano Technol, Taejon 305811, South Korea

来源：

HETEROATOM CHEMISTRY | 2012年 / 23卷 / 02期

基金：

新加坡国家研究基金会;

关键词：

ALPHA-AMINO PHOSPHONATES; ONE-POT SYNTHESIS; SOLVENT-FREE CONDITIONS; FACILE SYNTHESIS; CATALYST; EFFICIENT; ACID; DERIVATIVES; ALDEHYDES; TRIFLATE;

D O I：

10.1002/hc.20765

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of novel alpha-aminophosphonates have been prepared by one-pot three-component condensation in the presence of a zinc acetate (Zn(OAc)(2)center dot 2H(2)O) catalyst at 50 degrees C under solvent-free conditions with excellent yields. The major advantages of the present method are high yields, a short reaction time, and solvent-free reaction conditions. Their antimicrobial activity was evaluated, and some of them showed significant activity. (C) 2011 Wiley Periodicals, Inc. Heteroatom Chem 23:160165, 2012; View this article online at . DOI 10.1002/hc.20765

引用

页码：160 / 165

页数：6

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