Synthesis of 16-desmethylepothilone B: improved methodology for the rapid, highly selective and convergent construction of epothilone B and analogues

被引:33
作者
Nicolaou, KC
Hepworth, D
Finlay, MRV
King, NP
Werschkun, B
Bigot, A
机构
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
[3] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
关键词
D O I
10.1039/a809954e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
During a synthesis of 16-desmethylepothilone B new methods for the convergent and highly stereoselective synthesis of epothilone B and analogues were developed.
引用
收藏
页码:519 / 520
页数:2
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