Pityriasis Rubra Pilaris: Treatment with Biologics - A New Promising Therapy?

被引：20

作者：

Ivanova, Katja ^{[1
]}

Itin, Peter ^{[1
]}

Haeusermann, Peter ^{[1
]}

机构：

[1] Univ Basel Hosp, Dept Dermatol, CH-4031 Basel, Switzerland

来源：

DERMATOLOGY | 2012年 / 224卷 / 02期

关键词：

Pityriasis rubra pilaris; Biological agents; Tumor necrosis factor; VITAMIN-A; ALPHA; MANIFESTATION; INFLIXIMAB;

D O I：

10.1159/000337546

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Pityriasis rubra pilaris (PRP) includes a spectrum of rare chronic inflammatory disorders with papulosquamous eruptions of unknown cause. Different etiologies have been proposed such as vitamin A metabolism dysfunction, association with autoimmune disorders, infection or malignancies. However, PRP seems to be a polygenic skin disorder. Classical systemic treatment is empirical and includes retinoids and methotrexate; however, only few series on treatments exist. Recently there has been an increasing number of reports documenting that new biologicals and in particular TNF-alpha blockers are safe and effective. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：120 / 125

页数：6

共 50 条

[11] Photosensitive pityriasis rubra pilaris [J].

Mecinska-Jundzill, Kaja ;

Bialecka, Agnieszka ;

Adamska, Urszula ;

Skrzeczko-Kwela, Ewa ;

Czajkowski, Rafal .

POSTEPY DERMATOLOGII I ALERGOLOGII, 2016, 33 (03) :239-242

[12] Use of Biologics in Pityriasis Rubra Pilaris Refractory to First-Line Systemic Therapy: A Systematic Review [J].

Naidoo, Avee ;

Sibbald, Cathryn ;

Fleming, Patrick J. ;

Piguet, Vincent .

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY, 2020, 24 (01) :73-78

[13] Methotrexate treatment in a case of juvenile pityriasis rubra pilaris [J].

Boyd, Anne H. ;

Polcari, Ingrid C. .

PEDIATRIC DERMATOLOGY, 2018, 35 (01) :E62-E63

[14] Adalimumab for the Treatment of Pityriasis Rubra Pilaris: A Case Report [J].

Wassef, Cindy ;

Lombardi, Adriana ;

Rao, Babar K. .

CUTIS, 2012, 90 (05) :244-247

[15] Successful treatment with cyclosporine and guselkumab for pityriasis rubra pilaris [J].

Nishimura, Mai ;

Kondo, Makoto ;

Habe, Koji ;

Hayashi, Akinobu ;

Yamanaka, Keiichi .

CLINICAL CASE REPORTS, 2022, 10 (10)

[16] Pityriasis rubra pilaris secondary to viral infection [J].

Pawlik, Kacper ;

Jarosz-Chudek, Aleksandra ;

Dyduch, Grzegorz ;

Wojas-Pelc, Anna ;

Jaworek, Andrzej Kazimierz .

PRZEGLAD DERMATOLOGICZNY, 2023, 110 (05) :620-627

[17] Methotrexate Treatment for Pityriasis Rubra Pilaris: A Case Series and Literature Review [J].

Koch, Lukas ;

Schoffl, Clemens ;

Aberer, Werner ;

Massone, Cesare .

ACTA DERMATO-VENEREOLOGICA, 2018, 98 (05) :501-505

[18] Pityriasis rubra pilaris after vaccination [J].

Bennani, B. Naciri ;

Rouhou, H. Cheikh ;

Waton, J. ;

Cuny, J. -F. ;

Bassegoda, G. ;

Trechot, P. ;

Barbaud, A. ;

Schmutz, J. -L. .

ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2011, 138 (11) :753-756

[19] Pityriasis rubra pilaris in association with polyarthritis [J].

Nakafusa, J ;

Misago, N ;

Narisawa, Y .

DERMATOLOGY, 2002, 205 (03) :298-300

[20] Pulsed dye laser as an adjunctive treatment for therapy-resistant pityriasis rubra pilaris [J].

Lee, Justin ;

Iyengar, Sanjana ;

Zinn, Zachary .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020, 83 (06) :E391-E392

← 1 2 3 4 5 →