Electronic tuning of chiral diene ligands in iridium-catalyzed asymmetric 1,6-addition of arylboroxines to δ-aryl-α,β,γ,δ-unsaturated ketones

被引：51

作者：

Nishimura, Takahiro ^{[1
]}

Noishiki, Akira ^{[1
]}

Hayashi, Tamio ^{[1
]}

机构：

[1] Kyoto Univ, Dept Chem, Grad Sch Sci, Sakyo Ku, Kyoto 6068502, Japan

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 07期

关键词：

ENANTIOSELECTIVE 1,6-CONJUGATE ADDITION; GRIGNARD-REAGENTS; CONJUGATE ADDITION; BORONIC ACIDS; ARYL; TETRAFLUOROBENZOBARRELENES; 1,4-ADDITION;

D O I：

10.1039/c2cc16973h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric addition of arylboroxines to delta-aryl-alpha,beta,gamma,delta-unsaturated ketones proceeded in the presence of an iridium catalyst coordinated with a chiral diene ligand to give high yields of delta-diaryl ketones with very high enantioselectivity.

引用

页码：973 / 975

页数：3