Antimicrobial properties of natural carboxylic ionophores and their derivatives

被引：0
作者：
Stefanska, Joanna [1 ]
机构：
[1] Med Univ Warsaw, Zaklad Mikrobiol Farmaceut, PL-02007 Warsaw, Poland
来源：
POSTEPY MIKROBIOLOGII | 2015年 / 54卷 / 02期
关键词：
antibacterial activity; carboxylic ionophores; coccidiostatics; metal complexation; ANTIBACTERIAL ACTIVITY; IN-VITRO; CHEMICAL-MODIFICATION; X-RAY; CLOSTRIDIUM-PERFRINGENS; BIOLOGICAL-ACTIVITY; N-PHENYLAMIDE; FT-IR; MONENSIN; TRANSPORT;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Polyether ionophore antibiotics are a large group of natural substances, produced by various species of Streptomyces. These agents possess the ability to transport metal cations across lipid membranes, interfere with natural ion transport systems in cells and exhibit a variety of biological properties (antibacterial, antiparasitic, antiinflammatory or antiacancer). Several ionophores (e.g. lasalocid, monensin, narasin, salinomycin) are commercially applied as coccidiostatics in veterinary. The purpose of this report is to present an overview of antimicrobial activities of selected ionofores - lasalocid, monensin and salinomycin, and their derivatives.
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页码：175 / 183
页数：9
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