Occurrence of pharmaceuticals in a water supply system and related human health risk assessment

被引:297
作者
Gaffney, Vanessa de Jesus [1 ]
Almeida, Cristina M. M. [1 ,2 ]
Rodrigues, Alexandre [3 ]
Ferreira, Elisabete [3 ]
Benoliel, Maria Joao [3 ]
Cardoso, Vitor Vale [3 ]
机构
[1] Univ Lisbon, Fac Farm, iMed UL Inst Med & Pharmaceut Sci, P-1649003 Lisbon, Portugal
[2] Lab Bromatol & Qualidade Agua, P-1649003 Lisbon, Portugal
[3] Ernpresa Portuguesa Aguas Livres SA EPAL, Direcao Controlo Qualidade Agua, P-1800031 Lisbon, Portugal
关键词
Pharmaceuticals; Drinking water; Risk assessment; Indicators; DRINKING-WATER; SURFACE WATERS; TOXICOLOGICAL RELEVANCE; TRANSFORMATION; CHALLENGES; REMOVAL; ISSUES;
D O I
10.1016/j.watres.2014.10.027
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
A monitoring study of 31 pharmaceuticals along Lisbon's drinking Water supply system was implemented, which comprised the analysis of 250 samples including raw water (surface water and groundwater), and drinking water. Of the 31 pharmaceutical compounds, only sixteen were quantified in the analyzed samples, with levels ranging from 0.005 to 46 ng/L in raw water samples and 0.09-46 ng/L in drinking water samples. The human health risk assessment performed showed that appreciable risks to the consumer's health arising from exposure to trace levels of pharmaceuticals in drinking water are extremely unlikely, as RQs values were all below 0.001. Also, pharmaceuticals were selected as indicators to be used as a tool to control the quality of raw water and the treatment efficiency in the drinking water treatment plants. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:199 / 208
页数:10
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