Similar Outcomes of Kidney Transplantations Using Organs From Donors After Cardiac Death and Donors After Brain Death

被引:5
作者
Nakamura, Y. [1 ]
Kihara, Y. [1 ]
Yokoyama, T. [1 ]
Konno, O. [1 ]
Iwamoto, H. [1 ]
机构
[1] Tokyo Med Univ, Hachioji Med Ctr, Dept Kidney Transplantat Surg, Hachioji, Tokyo, Japan
关键词
EXPANDED-CRITERIA DONORS; SINGLE-CENTER EXPERIENCE; CIRCULATORY DEATH; RENAL-TRANSPLANTATION; PROGRAM;
D O I
10.1016/j.transproceed.2018.03.088
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background. To increase the number of cadaveric kidney transplants in Japan, it is necessary to proactively use organs from all donors. Since the revision of the Organ Transplant Law, the number of organ donors after cardiac death (DCD) has decreased but the number of organ donors after brain death (DBD) has increased; however, the number of donor organs and awareness of cadaveric transplantation have increased. Methods. At our institution, 28 patients underwent cadaveric kidney transplantation from January 2001 to December 2016. These patients were classified into 2 groups according to DBD or DCD. Furthermore, 10 patients received transplants from expanded criteria donors (ECD) and 18 received them from standard criteria donors (SCD). Results. Kidney graft survival and engraftment were observed for all patients. There were no significant differences in renal function at 6 months for DBD and DCD transplant recipients. Renal function at 1, 3, and 5 years and serum creatinine levels were better for the ECD group. Renal function at 5 years after transplantation was significantly better for the SCD group than for the ECD group; however, there was no difference in delayed graft function between the SCD and ECD groups. Comparisons of the 3 groups showed good renal function for transplants from DBDs, but there was no significant difference in survival rates. Conclusions. Results were good for all patients. There were no significant differences in outcomes of our patients who received transplants from ECD or SCD.
引用
收藏
页码:2404 / 2411
页数:8
相关论文
共 13 条
[1]   Long term outcomes of transplantation using kidneys from expanded criteria donors: prospective, population based cohort study [J].
Aubert, Olivier ;
Kamar, Nassim ;
Vernerey, Dewi ;
Viglietti, Denis ;
Martinez, Frank ;
Duong-Van-Huyen, Jean-Paul ;
Eladari, Dominique ;
Empana, Jean-Philippe ;
Rabant, Marion ;
Verine, Jerome ;
Rostaing, Lionel ;
Congy, Nicolas ;
Guilbeau-Frugier, Celine ;
Mourad, Georges ;
Garrigue, Valerie ;
Morelon, Emmanuel ;
Giral, Magali ;
Kessler, Michele ;
Ladriere, Marc ;
Delahousse, Michel ;
Glotz, Denis ;
Legendre, Christophe ;
Jouven, Xavier ;
Lefaucheur, Carmen ;
Loupy, Alexandre .
BMJ-BRITISH MEDICAL JOURNAL, 2015, 351
[2]   Renal Transplantation With Expanded Criteria Donors: The Experience of One Portuguese Center [J].
Ferrer, F. ;
Mota, A. ;
Alves, R. ;
Bastos, C. ;
Macario, F. ;
Figueiredo, A. ;
Santos, L. ;
Roseiro, A. ;
Parada, B. ;
Pratas, J. ;
Nunes, P. ;
Campos, M. .
TRANSPLANTATION PROCEEDINGS, 2009, 41 (03) :791-793
[3]   Survival of Kidney Allograft of Donors after Circulatory Death Is Similar to Donors after Brain Death: Experience in a Regional Program [J].
Gentil, M. A. ;
Castro, P. ;
Ballesteros, L. ;
Gracia-Guindo, M. C. ;
Cabello, M. ;
Mazuecos, M. A. ;
Rodriguez-Benot, A. ;
Gonzalez-Corvillo, C. ;
Borrego, J. ;
Ortega, A. O. ;
Alonso, M. .
TRANSPLANTATION PROCEEDINGS, 2015, 47 (09) :2572-2574
[4]   Study of Cadaveric Kidney Transplantation: A Single Center Experience [J].
Kihara, Y. ;
Nakamura, Y. ;
Yokoyama, T. ;
Konno, O. ;
Iwamoto, H. ;
Kawachi, S. .
TRANSPLANTATION PROCEEDINGS, 2016, 48 (03) :725-728
[5]   Non-Heart-Beating Donor Program: Results After 3 Years of Experience [J].
Martin-Villen, L. ;
Revuelto-Rey, J. ;
Aldabo-Pallas, T. ;
Correa-Chamorro, E. ;
Gallego-Corpa, A. ;
del Portal-Ruiz Granados, P. Ruiz ;
Roncero-Rodriguez, M. A. ;
Egea-Guerrero, J. J. .
TRANSPLANTATION PROCEEDINGS, 2015, 47 (09) :2567-2569
[6]   Kidneys donated after cardiac death are acceptable [J].
Morris, Peter J. .
LANCET, 2010, 376 (9749) :1276-1278
[7]   Brain death and its influence on donor organ quality and outcome after transplantation [J].
Pratschke, J ;
Wilhelm, MJ ;
Kusaka, M ;
Basker, M ;
Cooper, DKC ;
Hancock, WW ;
Tilney, NL .
TRANSPLANTATION, 1999, 67 (03) :343-348
[8]   Transplantation of kidneys from expanded criteria donors [J].
Ratner, LE ;
Kraus, E ;
Magnuson, T ;
Bender, JS .
SURGERY, 1996, 119 (04) :372-377
[9]   The expanded criteria donor dilemma in cadaveric renal transplantation. [J].
Schnitzler, MA ;
Whiting, JF ;
Brennan, DC ;
Lin, G ;
Chapman, W ;
Lowell, J ;
Boxerman, S ;
Hardinger, KL ;
Kalo, Z .
TRANSPLANTATION, 2003, 75 (12) :1940-1945
[10]   Kidney donation after circulatory death (DCD): state of the art [J].
Summers, Dominic M. ;
Watson, Christopher J. E. ;
Pettigrew, Gavin J. ;
Johnson, Rachel J. ;
Collett, David ;
Neuberger, James M. ;
Bradley, J. Andrew .
KIDNEY INTERNATIONAL, 2015, 88 (02) :241-249