A case of active peri-stent inflammation after sirolimus-eluting stent implantation

被引:4
作者
Kurosawa, Takafumi [1 ]
Kotani, Jun-ichi [2 ]
Matsuyama, Taka-aki [1 ]
Ishibashi-Ueda, Hatsue [1 ]
机构
[1] Natl Cerebral & Cardiovasc Ctr, Div Pathol, Suita, Osaka, Japan
[2] Osaka Univ, Grad Sch Med, Div Cardiovasc Med, Suita, Osaka 5650871, Japan
关键词
Drug-eluting stent; Inflammation; Pathology; Percutaneous coronary intervention; INTRAVASCULAR ULTRASOUND ANALYSIS; ROTATIONAL ATHERECTOMY; MALAPPOSITION; THROMBOSIS; APPOSITION; ANGIOPLASTY;
D O I
10.1007/s00380-013-0465-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report an autopsy case of a coronary aneurysm with massive adventitial inflammation post-percutaneous coronary intervention with sirolimus-eluting stent (SES) insertion in the left circumflex (LCX) coronary artery for ischemic heart disease 3 years prior to death. The internal elastic membrane was disrupted opposite the site of the eccentric LCX plaque due to injury during stenting, and the adventitia showed massive inflammatory cell infiltration, mainly consisting of eosinophils. The LCX showed aneurysmal dilatation with inflammatory cell infiltration. Inappropriate SES implantation attracted chronic inflammation. Chronic inflammation can lead to the development of coronary artery aneurysms.
引用
收藏
页码:270 / 273
页数:4
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