Treatment-resistant schizophrenia

被引：146
作者：
Elkis, Hello
机构：
[1] Univ Sao Paulo, Sch Med, Dept Psychiat, BR-05403010 Sao Paulo, Brazil
[2] Univ Sao Paulo, Sch Med, Inst Psychiat, BR-05403010 Sao Paulo, Brazil
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2007年 / 30卷 / 03期
关键词：
D O I：
10.1016/j.psc.2007.04.001
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
This article opens with a brief history of pharmacologic treatment of schizophrenia. It then discusses the definition and treatment of treatment-resistant schizophrenia, with particular attention to clinical, biological and neuroimaging correlates, as well as the best treatment options, including the use of clozapine in patients who meet the definition of treatment-resistant schizophrenia.
引用
收藏
页码：511 / +
页数：24
相关论文
共 150 条
[51]   An exploratory open-label trial of aripiprazole as an adjuvant to clozapine therapy in chronic schizophrenia [J].
Henderson, DC ;
Kunkel, L ;
Nguyen, DD ;
Borba, CP ;
Daley, TB ;
Louie, PM ;
Freudenreich, O ;
Cather, C ;
Evins, AE ;
Goff, DC .
ACTA PSYCHIATRICA SCANDINAVICA, 2006, 113 (02) :142-147
[52]   Switching from clozapine to olanzapine in treatment-refractory schizophrenia: Safety, clinical efficacy, and predictors of response [J].
Henderson, DC ;
Nasrallah, RA ;
Goff, DC .
JOURNAL OF CLINICAL PSYCHIATRY, 1998, 59 (11) :585-588
[53]  
Henna J, 1999, SCHIZOPHR RES, V36, P281
[54]   Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations [J].
Hoffman, RE ;
Hawkins, KA ;
Gueorguieva, R ;
Boutros, NN ;
Rachid, F ;
Carroll, K ;
Krystal, JH .
ARCHIVES OF GENERAL PSYCHIATRY, 2003, 60 (01) :49-56
[55]   Temporoparietal transcranial magnetic stimulation for auditory hallucinations: Safety, efficacy and moderators in a fifty patient sample [J].
Hoffman, RE ;
Gueorguieva, R ;
Hawkins, KA ;
Varanko, M ;
Boutros, NN ;
Wu, YT ;
Carroll, K ;
Krystal, JH .
BIOLOGICAL PSYCHIATRY, 2005, 58 (02) :97-104
[56]   Clozapine alone versus clozapine and risperidone with refractory schizophrenia [J].
Honer, WG ;
Thornton, AE ;
Chen, EYH ;
Chan, RCK ;
Wong, JOY ;
Bergmann, A ;
Falkai, P ;
Pomarol-Clotet, E ;
McKenna, PJ ;
Stip, E ;
Williams, R ;
MacEwan, GW ;
Wasan, K ;
Procyshyn, R ;
Leung, SP ;
Wong, JOY ;
Rodriguez, JP ;
Lalonde, P ;
Stip, E ;
Pomarol-Clotet, E ;
McKenna, PJ ;
MacEwan, GW ;
Chen, EYH ;
Chan, RCK ;
Flynn, SW ;
Altman, S ;
Honer, WG ;
Thornton, AE ;
Procyshyn, R ;
Huckin, S ;
Au, T ;
Boudreau, A ;
Humphries, B ;
Williams, R ;
Wasan, K ;
Bergmann, A ;
Falkai, P ;
Wobrock, T ;
Wollny, H .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (05) :472-482
[57]  
HONER WG, 1995, NEUROPSYCHOPHARMACOL, V13, P85, DOI 10.1016/0893-133X(95)00017-8
[58]   TREATMENT-RESISTANT SCHIZOPHRENIA - CONTROLLED-STUDY OF MODERATE-DOSE AND HIGH-DOSE THIOTHIXENE [J].
HUANG, CC ;
GERHARDSTEIN, RP ;
KIM, DY ;
HOLLISTER, L .
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 1987, 2 (01) :69-75
[59]   THERAPEUTIC STUDIES IN THERAPY RESISTANT SCHIZOPHRENIC PATIENTS [J].
ITIL, TM ;
KESKINER, A ;
FINK, M .
COMPREHENSIVE PSYCHIATRY, 1966, 7 (06) :488-&
[60]   Validation of polypharmacy process measures in inpatient schizophrenia care [J].
Janssen, B ;
Weinmann, S ;
Berger, M ;
Gaebel, W .
SCHIZOPHRENIA BULLETIN, 2004, 30 (04) :1023-1033
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