Impact of the home indoor environment on adult asthma and rhinitis

被引:49
作者
Blanc, PD
Eisner, MD
Katz, PP
Yen, IH
Archea, C
Earnest, G
Janson, S
Masharani, UB
Quinlan, PJ
Hammond, SK
Thorne, PS
Balmes, JR
Trupin, L
Yelin, EH
机构
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Inst Cardiovasc Res, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Sch Nursing, Dept Community Hlth Syst, San Francisco, CA 94143 USA
[4] Univ Calif Berkeley, Sch Publ Hlth, Div Environm Hlth Sci, Berkeley, CA 94720 USA
[5] Univ Iowa, Coll Publ Hlth, Dept Occupat & Environm Hlth, Iowa City, IA USA
关键词
D O I
10.1097/01.jom.0000158708.32491.9d
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: We sought to study the combined effects of multiple home indoor environmental exposures in adult asthma and rhinitis. Methods: We studied 226 adults with asthma and rhinitis by structured interviews and home assessments. Environmental factors included dust allergen, endotoxin and glucan concentrations, and indoor air quality (IAQ) variables. Outcomes included forced expiratory volume in I second (FEV1) percent predicted, Severity of Asthma Score (SAS), Short-Form (SF)-12 Physical Component Scale (PCS), and asthma Quality of Life (QOL) score. Results: House dust-associated exposures together with limited IAQ variables were related to FEV1 % predicted (R-2 = 0.24; P = 0.0001) and SAS (R-2 = 0.18; P = 0.007). IAQ and limited dust variables were associated with SF-12 PCS (R-2 = 0.15; P = 0.02), but not QOL (R-2 = 0.13; P = 0.16). Conclusions: The home environment is strongly linked to lung function, health status, and disease severity, in adult asthma and rhinitis.
引用
收藏
页码:362 / 372
页数:11
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