Clinical utility of novel biosensing platform: Diagnosis of coronavirus SARS-CoV-2 at point of care

被引:2
作者
Aljabali, Alaa A. A. [1 ]
Pal, Kaushik [2 ]
Serrano-Aroca, Angel [3 ]
Takayama, Kazuo [4 ]
Dua, Kamal [5 ]
Tambuwala, Murtaza M. [6 ]
机构
[1] Yarmouk Univ, Fac Pharm, Dept Pharmaceut & Pharmaceut Technol, Irbid 566, Jordan
[2] Univ Fed Rio de Janeiro, LaBioS Ctr Tecnol, Lab Biopolimeros & Sensores, BR-21941901 Rio De Janeiro, RJ, Brazil
[3] Catholic Univ Valencia San Vicente Martir, Translat Res Ctr San Alberto Magno, Biomat & Bioengn Lab, C Guillem de Castro 94, Valencia 46001, Spain
[4] Kyoto Univ, Ctr iPS Cell Res & Applicat, Kyoto 6068507, Japan
[5] Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, Ultimo, NSW 2007, Australia
[6] Ulster Univ, Sch Pharm & Pharmaceut Sci, Coleraine BT52 1SA, Londonderry, North Ireland
关键词
SARS-CoV-2; Nanomaterials; Biosensors; Polymerase chain reaction; COVID-19 clinical diagnostics;
D O I
10.1016/j.matlet.2021.130612
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Early detection is the first step in the fight against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, an efficient, rapid, selective, specific, and inexpensive SARS-CoV-2 diagnostic method is the need of the hour. The reverse transcription-polymerase chain reaction (RT-PCR) technology is massively utilized to detect infection with SARS-CoV-2. However, scientists continue to strive to create enhanced technology while continually developing nanomaterial-enabled biosensing methods that can provide new methodologies, poten-tially fulfilling the present demand for rapid and early identification of coronavirus disease 2019 (COVID-19) patients. Our review presents a summary of the recent diagnosis of SARS-CoV-2 of COVID-19 pandemic and nanomaterial-available biosensing methods. Although limited research on nanomaterials-based nanosensors has been published, allowing for biosensing approaches for diagnosing SARS-CoV-2, this study highlights nano -materials that provide an enhanced biosensing strategy and potential processes that lead to COVID-19 diagnosis.
引用
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页数:4
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