Does midtrimester cervical length ≥25 mm predict preterm birth in high-risk women?

被引:9
作者
Owen, John [1 ]
Szychowski, Jeff M. [2 ]
Hankins, Gary [3 ]
Iams, Jay D. [4 ]
Sheffield, Jeanne S. [5 ]
Perez-Delboy, Annette [6 ]
Berghella, Vincenzo [7 ]
Wing, Deborah A. [8 ]
Guzman, Edwin R. [9 ]
机构
[1] Univ Alabama Birmingham, Dept Obstet & Gynecol, Div Maternal Fetal Med, Birmingham, AL 35294 USA
[2] Univ Alabama Birmingham, Dept Biostat, Birmingham, AL 35294 USA
[3] Univ Texas Med Branch, Dept Obstet & Gynecol, Galveston, TX USA
[4] Ohio State Univ, Med Ctr, Dept Obstet & Gynecol, Columbus, OH 43210 USA
[5] Univ Texas SW Med Ctr Dallas, Dept Obstet & Gynecol, Dallas, TX 75390 USA
[6] Columbia Univ, Coll Phys & Surg, Dept Obstet & Gynecol, New York, NY USA
[7] Thomas Jefferson Univ, Div Maternal Fetal Med, Dept Obstet & Gynecol, Philadelphia, PA 19107 USA
[8] Univ Calif Irvine, Dept Obstet & Gynecol, Irvine, CA 92717 USA
[9] St Peters Univ Hosp, Dept Obstet & Gynecol, New Brunswick, NJ USA
关键词
cervical length; preterm birth prediction; prior preterm birth; vaginal sonography; CERCLAGE; PREVENTION; ULTRASONOGRAPHY; DILATATION; SONOGRAPHY; DELIVERY; TRIAL;
D O I
10.1016/j.ajog.2010.06.025
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: We sought to assess pregnancy outcome along a continuum of cervical lengths (CLs) >= 25 mm. STUDY DESIGN: We conducted planned secondary analysis of a randomized cerclage trial of women with prior spontaneous preterm birth 17(0)-34(6/7) weeks. Outcomes of women who maintained CLs >= 25 mm were analyzed. Women with CLs <25 mm randomized to no cerclage comprised an internal comparison group. RESULTS: Of 1014 screened, 153 had CL <25 mm, and 672 had CL >= 25 mm. Birth <35 weeks occurred in 16% of the >= 25 mm cohort. The relationship between CLs >= 25 mm and birth gestational age was null ( P = .15). In the <25 mm group, progressively shorter CLs predicted birth <35 weeks ( P < .001); this relationship was null in the >= 25 mm group ( P = .17). CONCLUSION: The continuum of CLs >= 25 mm measured between 16(0/7)-22(6/7) weeks does not predict gestational length in women with prior spontaneous preterm birth.
引用
收藏
页码:393.e1 / 393.e5
页数:5
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