Preparation and Characterization of Genipin-Crosslinked Chitosan/Poly(ethylene glycol) Composites Films

被引:0
作者
Liu, Yangshuo [1 ]
Yu, Fucheng [1 ]
机构
[1] Lanzhou Univ Technol, Sch Mat Sci & Engn, Lanzhou 730050, Peoples R China
关键词
Chitosan; Poly(ethylene glycol); Mechanical properties; Genipin; MECHANICAL-PROPERTIES; CHITOSAN HYDROGELS; MEMBRANE; BLENDS;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chitosan/poly(ethylene glycol) interpenetrating networks were prepared using solution casting technique. A naturally occurring and nontoxic cross-linking agent, genipin, was used to form the genipin-crosslinked chitosan and chitosan/poly(ethylene glycol) blends networks, where four types of poly(ethylene glycol) were used. Genipin overcomes the problem of physiological toxicity inherent in the use of some common synthetic chemicals as cross-linking agents. It was shown that the properties of films made by blending chitosan with four types of poly(ethylene glycol). The swelling ratio increase with the increase of molecule weight of poly(ethylene glycol). The mechanical properties were slightly improved with the proper amount of molecule weight of poly(ethylene glycol). The surface properties of the films were also examined by contact angles. The results showed that in water, the cross-linked chitosan and chitosan/poly(ethylene glycol) blends were more hydrophobic with the decrease of the molecular weight of poly(ethylene glycol).
引用
收藏
页码:2020 / 2024
页数:5
相关论文
共 29 条
[11]   Novel chitosan-based films cross-linked by genipin with improved physical properties [J].
Jin, J ;
Song, M ;
Hourston, DJ .
BIOMACROMOLECULES, 2004, 5 (01) :162-168
[12]   Nitrous acid pretreatment of tendon xenografts cross-linked with glutaraldehyde and sterilized with gamma irradiation [J].
Johnson, KA ;
Rogers, GJ ;
Roe, SC ;
Howlett, CR ;
Clayton, MK ;
Milthorpe, BK ;
Schindhelm, K .
BIOMATERIALS, 1999, 20 (11) :1003-1015
[13]   Improvement in ductility of chitosan through blending and copolymerization with PEG: FTIR investigation of molecular interactions [J].
Kolhe, P ;
Kannan, RM .
BIOMACROMOLECULES, 2003, 4 (01) :173-180
[14]   Cross-Linked Chitosan/Chitin Crystal Nanocomposites with Improved Permeation Selectivity and pH Stability [J].
Mathew, Aji P. ;
Laborie, Marie-Pierre G. ;
Oksman, Kristiina .
BIOMACROMOLECULES, 2009, 10 (06) :1627-1632
[15]   Synthesis, swelling behavior, and biocompatibility of novel physically cross-linked polyurethane-block-poly(glycerol methacrylate) hydrogels [J].
Mequanint, K ;
Patel, A ;
Bezuidenhout, D .
BIOMACROMOLECULES, 2006, 7 (03) :883-891
[16]   In vitro evaluation of a chitosan membrane cross-linked with genipin [J].
Mi, FL ;
Tan, YC ;
Liang, HC ;
Huang, RN ;
Sung, HW .
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2001, 12 (08) :835-850
[17]   Genipin-crosslinked chitosan hydrogels as biomedical and pharmaceutical aids [J].
Muzzarelli, Riccardo A. A. .
CARBOHYDRATE POLYMERS, 2009, 77 (01) :1-9
[18]  
Roberts GA, 1992, CHITIN CHEM, DOI DOI 10.1007/978-1-349-11545-7
[19]   Formulation and characterization of chitosan-based hydrogel films having both temperature and pH sensitivity [J].
Sun, Guoming ;
Zhang, Xian-Zheng ;
Chu, Chih-Chang .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2007, 18 (08) :1563-1577
[20]   Effects of drying methods and plasticizer concentration on some physical and mechanical properties of edible chitosan films [J].
Thakhiew, Wasina ;
Devahastin, Sakamon ;
Soponronnarit, Somchart .
JOURNAL OF FOOD ENGINEERING, 2010, 99 (02) :216-224