Design, synthesis, and testing of Kv1.3 blockers based on diphenoxylate

被引：0
|
作者：
Nguyen, William [1 ]
Wulff, Heike
Howard, Brittany [1 ]
White, Paul [1 ]
Thompson, Philip [1 ]
Manallack, David [1 ]
机构：
[1] Monashi Univ, Melbourne, Vic, Australia
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 242卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
121-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate
    Nguyen, William
    Howard, Brittany L.
    Jenkins, David P.
    Wulff, Heike
    Thompson, Philip E.
    Manallack, David T.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (23) : 7106 - 7109
  • [2] Design and synthesis of human T cell Kv1.3 potassium channel blockers.
    Lew, A
    Chamberlin, AR
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 218 : U917 - U917
  • [3] Kv1.3 blockers for treatment of autoimmune diseases
    Tasler, Stefan
    Dreker, Tobias
    Kraus, Juergen
    Hamm, Svetlana
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [4] Novel Kv1.3 blockers for the treatment of autoimmune diseases
    Kudryashova, K.
    Kuzmenkov, A.
    Nekrasova, O.
    Feofanov, A.
    Grishin, E.
    Vassilevski, A.
    FEBS JOURNAL, 2014, 281 : 149 - 149
  • [5] Use of Kv1.3 Blockers for Inflammatory Skin Conditions
    Nguyen, W.
    Howard, B. L.
    Neale, D. S.
    Thompson, P. E.
    White, P. J.
    Wulff, H.
    Manallack, D. T.
    CURRENT MEDICINAL CHEMISTRY, 2010, 17 (26) : 2882 - 2896
  • [6] Benzamide derivatives as blockers of Kv1.3 ion channel
    Miao, SW
    Bao, JM
    Garcia, ML
    Goulet, JL
    Hong, XF
    Kaczorowski, GJ
    Kayser, F
    Koo, GC
    Kotliar, A
    Schmalhofer, WA
    Shah, K
    Sinclair, PJ
    Slaughter, RS
    Springer, MS
    Staruch, MJ
    Tsou, NN
    Wong, F
    Parsons, WH
    Rupprecht, KM
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (06) : 1161 - 1164
  • [7] Design and synthesis of new structural class of Kv1.3 inhibitors
    Gubic, S.
    Toplak, Z.
    Hendrickx, L.
    Dobricic, V.
    Tytgat, J.
    Tomasic, T.
    Masic, L. Peterlin
    FEBS OPEN BIO, 2021, 11 : 425 - 425
  • [8] Novel Kv1.3 blockers for immunosuppression: WO2012155199
    William Nguyen
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2013, 23 (11) : 1511 - 1516
  • [9] Targeting effector memory T-cells with Kv1.3 blockers
    Wulff, Heike
    Pennington, Michael
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2007, 10 (04) : 438 - 445
  • [10] Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3:: Synthesis and immunosuppressive activity
    Baell, JB
    Gable, RW
    Harvey, AJ
    Toovey, N
    Herzog, T
    Hänsel, W
    Wulff, H
    JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (09) : 2326 - 2336
12345