Effects of short-term supplementation with folic acid on different oxidative stress parameters in patients with hypertension

被引：9
|
作者：
Stiefel, P
Argüelles, S
García, S
Jiménez, L
Aparicio, R
Carneado, J
Machado, A
Ayala, A
机构：
[1] Univ Seville, Fac Farm, Dept Bioquim Bromatol Toxicol, E-41012 Seville, Spain
[2] Hosp Univ Virgen Rocio, Dept Med Interna, Unidad Hipertens & Lipidos, Seville, Spain
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 2005年 / 1726卷 / 02期
关键词：
folic acid; hypertension; oxidative stress; homocysteine; oxidative stress marker; TBARS; carbonyl group; lipid peroxide;
D O I：
10.1016/j.bbagen.2005.07.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Oxidative stress seems to play an important role in the pathophysiology of essential hypertension. Due to its antioxidant features, we studied the protective action of folic acid in hypertensive patients, their food supplemented for 2 weeks with this vitamin. Several oxidative stress parameters were measured in the serum of these patients. The results show that folic acid supplementation improves levels of oxidative stress markers in individuals with hypertension, overall in those patients whose initial parameter values were highest. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：152 / 159
页数：8
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