Two New Cembranes from a Formosan Soft Coral Sinularia facile

被引：13

作者：

Chen, Bo-Wei ^{[1
]}

Su, Jui-Hsin ^{[2
]}

Dai, Chang-Feng ^{[3
]}

Sung, Ping-Jyun ^{[2
,4
]}

Wu, Yang-Chang ^{[5
,6
,7
]}

Lin, Ying-Ting ^{[8
]}

Sheu, Jyh-Horng ^{[1
,9
]}

机构：

[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung 80424, Taiwan

[2] Natl Museum Marine Biol & Aquarium, Taiwan Coral Res Ctr, Checheng 944, Pingtung, Taiwan

[3] Natl Taiwan Univ, Inst Oceanog, Taipei 112, Taiwan

[4] Natl Dong Hwa Univ, Grad Inst Marine Biol, Checheng 944, Pingtung, Taiwan

[5] China Med Univ, Grad Inst Integrated Med, Coll Chinese Med, Taichung 404, Taiwan

[6] China Med Univ Hosp, Nat Med Prod Res Ctr, Taichung 404, Taiwan

[7] China Med Univ Hosp, Ctr Mol Med, Taichung 404, Taiwan

[8] Kaohsiung Med Univ, Dept Biotechnol, Coll Life Sci, Kaohsiung 804, Taiwan

[9] Natl Sun Yat Sen Univ, Asia Pacific Ocean Res Ctr, Kaohsiung 804, Taiwan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2011年 / 84卷 / 12期

关键词：

TUMOR-CELL-LINES; ASSAY;

D O I：

10.1246/bcsj.20110186

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new hydroxycembranes 1 and 2 and two known epoxycembrane 3 and isocembrol 4 have been isolated from a Formosan soft coral Sinularia facile. The structures of new metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1-4 against the proliferation of a limited panel of cancer cell lines was measured.

引用

页码：1371 / 1373

页数：3

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