Synthesis of 2-aminofurans and 2-unsubstituted furans via carbenoid-mediated [3+2] cycloaddition

被引：91

作者：

Jiang, Yaojia ^{[1
]}

Khong, Vanessa Zhong Yue ^{[1
]}

Lourdusamy, Emmanuvel ^{[1
]}

Park, Cheol-Min ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 25期

关键词：

POLYSUBSTITUTED FURANS; EFFICIENT SYNTHESIS; PYRROLES;

D O I：

10.1039/c2cc18139h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient dual synthetic manifold for 2-aminofurans and 2-unsubstituted furans has been developed. The carbenoid-mediated [3 + 2] cycloaddition of copper carbenoids with enamines provides 2-amino-2,3-dihydrofurans which serve as common intermediates for both 2-aminofurans and 2-unsubstituted furans.

引用

页码：3133 / 3135

页数：3

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