Cu(II) ionic liquid promoted Simple and Economical Synthesis of 1,4-disubstituted-1,2,3-triazoles with Low Catalyst Loading

被引：5

作者：

Phukan, Parmita ^{[1
]}

Kulshrestha, Akshay ^{[2
]}

Kumar, Arvind ^{[2
]}

Chakraborti, Srijita ^{[3
]}

Chattopadhyay, Pronobesh ^{[3
]}

Sarma, Diganta ^{[1
]}

机构：

[1] Dibrugarh Univ, Dept Chem, Dibrugarh, Assam, India

[2] Council Sci & Ind Res CSIR, Cent Salt & Marine Chem Res Inst, Acad Sci & Innovat Res AcSIR, Bhavnagar, Gujarat, India

[3] Def Res Lab, Tezpur, Assam, India

来源：

JOURNAL OF CHEMICAL SCIENCES | 2021年 / 133卷 / 04期

关键词：

Green chemistry; ionic liquid; CuAAC; non-toxic; low metal loading; ALKYNE CYCLOADDITION REACTIONS; ASYMMETRIC HYDROGENATION; REGIOSELECTIVE SYNTHESIS; AEROBIC OXIDATION; GREEN ROUTE; COMPLEXES; COPPER; 1,2,3-TRIAZOLES; EFFICIENT; CHLORIDE;

D O I：

10.1007/s12039-021-01980-9

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this work, we have described a very simple and low metal loading copper-based ionic liquid as solvent and catalyst for regioselective synthesis of 1,4-disubstituted-1,2,3-triazoles. The proposed protocol proved its efficiency by showing excellent tolerance to a large array of electronically diverse substrates without the use of the external base, solvent and ligands. Moreover, from cytotoxicity analysis the catalyst was found to be non-toxic in nature due to extremely low loading of copper metal (0.1 mol %).

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页数：8

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共 51 条

[1] Synthesis and biological evaluation of novel 1,2,3-triazole derivatives as anti-tubercular agents [J].

Ali, Abdul Aziz ;

Gogoi, Dhrubajyoti ;

Chaliha, Amrita K. ;

Buragohain, Alak K. ;

Trivedi, Priyanka ;

Saikia, Prakash J. ;

Gehlot, Praveen S. ;

Kumar, Arvind ;

Chaturvedi, Vinita ;

Sarma, Diganta .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (16) :3698-3703

[2] [Bmim]OH mediated Cu-catalyzed azide-alkyne cycloaddition reaction: A potential green route to 1,4-disubstituted 1,2,3-triazoles [J].

Ali, Abdul Aziz ;

Konwar, Manashjyoti ;

Chetia, Mitali ;

Sarma, Diganta .

TETRAHEDRON LETTERS, 2016, 57 (50) :5661-5665

[3] Urea assisted copper(I)-catalyzed azide-alkyne cycloaddition reactions in water [J].

Ali, Abdul Aziz ;

Chetia, Mitali ;

Sarma, Diganta .

TETRAHEDRON LETTERS, 2016, 57 (15) :1711-1714

[4] (DHQD)2PHAL ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition reactions in water at room temperature [J].

Ali, Abdul Aziz ;

Chetia, Mitali ;

Saikia, Prakash J. ;

Sarma, Diganta .

RSC ADVANCES, 2014, 4 (110) :64388-64392

[5] Synthesis of an ionic liquid with an iron coordination cation [J].

Anderson, Travis M. ;

Ingersoll, David ;

Rose, Alyssa J. ;

Staiger, Chad L. ;

Leonard, Jonathan C. .

DALTON TRANSACTIONS, 2010, 39 (37) :8609-8612

[6] Copper(I)-Containing Ionic Liquids for High-Rate Electrodeposition [J].

Brooks, Neil R. ;

Schaltin, Stijn ;

Van Hecke, Kristof ;

Van Meervelt, Luc ;

Binnemans, Koen ;

Fransaer, Jan .

CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (18) :5054-5059

[7] Asymmetric hydrogenation and catalyst recycling using ionic liquid and supercritical carbon dioxide [J].

Brown, RA ;

Pollet, P ;

McKoon, E ;

Eckert, CA ;

Liotta, CL ;

Jessop, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (06) :1254-1255

[8] Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [J].

Campestre, Cristina ;

Locatelli, Marcello ;

Guglielmi, Paolo ;

De Luca, Elisa ;

Bellagamba, Giuseppe ;

Menta, Sergio ;

Zengin, Gokhan ;

Celia, Christian ;

Di Marzio, Luisa ;

Carradori, Simone .

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2017, 32 (01) :1053-1063

[9] Click Chemistry in Materials Synthesis: The Beginning [J].

Diaz Diaz, David .

MACROMOLECULAR SYMPOSIA, 2015, 358 (01) :10-20

[10] The art of using ionic liquids in the synthesis of inorganic nanomaterials [J].

Duan, Xiaochuan ;

Ma, Jianmin ;

Lian, Jiabiao ;

Zheng, Wenjun .

CRYSTENGCOMM, 2014, 16 (13) :2550-2559

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