共 15 条
Risk factors of long-term alopecia after pulsed-dye laser treatment for infantile scalp hemangiomas: A retrospective study
被引:1
作者:

Yang, Liu
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Zhou, Nuoya
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h-index: 0
机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Alamgir, Mahin
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h-index: 0
机构:
Rutgers State Univ, Dept Dermatol, New Brunswick, NJ USA Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Wang, Zhen
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机构:
Tongji Med Coll, Dept Epidemiol & Stat, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Gao, Yaoying
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Li, Yan
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

An, Xiangjie
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Dong, Liyun
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Zhang, Yamin
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机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Yang, Jing
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h-index: 0
机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China

Tao, Juan
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h-index: 0
机构:
Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
机构:
[1] Huazhong Univ Sci & Technol HUST, Union Hosp, Tongji Med Coll, Dept Dermatol, 1277 Jiefang Ave, Wuhan 430022, Peoples R China
[2] Hubei Engn Res Ctr Skin Repair & Theranost, Wuhan, Peoples R China
[3] Rutgers State Univ, Dept Dermatol, New Brunswick, NJ USA
[4] Tongji Med Coll, Dept Epidemiol & Stat, Wuhan, Peoples R China
关键词:
alopecia;
hemangioma;
infant;
pulsed-dye laser;
risk;
VASCULAR-LESIONS;
THERAPY;
SKIN;
D O I:
10.1111/1346-8138.16359
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
Pulsed-dye laser (PDL), as an effective and frequently-used treatment modality for infantile hemangiomas (IH), could render patients at risk of developing long-term alopecia. Data on alopecia caused by PDL treatment remain scant and the contributing factors are not clear. Our objective was to identify the risk factors associated with long-term alopecia resulting from PDL treatment for scalp IH. We conducted a retrospective study incorporating patients with IH diagnosis and PDL intervention via thoroughly reviewing the clinical database of the dermatology department. Scalp IH patients were further screened and their medical records were collected. Long-term alopecia was defined as no signs of terminal hair regrowth for at least 2 years in this study. Of the 1293 IH patients, 47 (14 boys and 33 girls) with a mean age of 4.5 months (standard deviation, 3.2) were diagnosed as scalp IH and had subsequently undergone PDL treatments. Hair growth in the treatment area of 18 patients (38.3%) nearly returned to normal, 22 patients (46.8%) had varying degrees of hair loss, and seven patients (14.9%) had no hair regrowth (long-term alopecia). Compared with the older patients receiving treatment, IH patients younger than 3 months who started PDL treatment had a higher risk of developing long-term alopecia (odds ratio, 30.833; 95% confidence interval, 4.079-232.025; p = 0.01). The total number of PDL sessions, post-treatment blisters, and location of IH were not shown to be significantly associated with the development of long-term alopecia. Collectively, our study provides an important insight into curating treatments for IH in infants younger than 3 months. PDL treatments for scalp IH may perhaps be avoided or delayed to prevent the development of treatment-associated long-term alopecia.
引用
收藏
页码:661 / 665
页数:5
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机构:
Kanto Cent Hosp, Dept Pediat, Tokyo, Japan Kanto Cent Hosp, Dept Dermatol, Tokyo, Japan

Katori, Tatsuo
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机构:
Showa Gen Hosp, Dept Pediat, Tokyo, Japan Kanto Cent Hosp, Dept Dermatol, Tokyo, Japan