Synthesis of PdII Complexes Bearing pNHC Ligands by Oxidative Addition of 8-Halogenotheophyllines and 8-Bromoadenine to Pd0

被引：14

作者：

Blumenberg, Jonas ^{[1
]}

Wilm, Lukas F. B. ^{[1
]}

Hahn, F. Ekkehardt ^{[1
]}

机构：

[1] Westfalische Wilhelms Univ Munster, Inst Anorgan & Analyt Chem, D-48149 Munster, Germany

来源：

ORGANOMETALLICS | 2020年 / 39卷 / 08期

关键词：

N-HETEROCYCLIC CARBENES; PALLADIUM(II); METALATION; STABILITY;

D O I：

10.1021/acs.organomet.0c00046

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Various 8-halogenotheophyllines (halogen = CI, Br, I) were selectively C8 metalated by an oxidative addition of the C8- halogen bond to [Pd(PPh3)(4)] to give the Pd-II azolato complexes [1]-[3]. The complexes were protonated at the N9 nitrogen atom to yield the NH,NH-NHC (pNHC) complexes [4]BF4 -[6]BF4. Due to the unsymmetrical nature of the backbone of the theophylline-derived pNHC ligands, two NH resonances were observed by H-1 NMR spectroscopy. In addition, 8-bromoadenine was also regioselectively C8 metalated via an oxidative addition of the C8-Br bond to [Pd(PPh3)(4)] in the presence of the proton source pyridinium tetrafluoroborate to give [7]BF4.

引用

页码：1281 / 1287

页数：7

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