Virulence, persistence and dissemination of Mycoplasma bovis

被引:107
作者
Buerki, Sibylle [1 ,2 ]
Frey, Joachim [1 ]
Pilo, Paola [1 ]
机构
[1] Univ Bern, Inst Vet Bacteriol, Vetsuisse Fac, CH-3012 Bern, Switzerland
[2] Univ Bern, Grad Sch Cellular & Biomed Sci, CH-3012 Bern, Switzerland
关键词
Mycoplasma bovis; Virulence attributes; Dissemination; Persistence; VARIABLE SURFACE LIPOPROTEINS; IN-SITU HYBRIDIZATION; VIRAL DIARRHEA VIRUS; RESPIRATORY-DISEASE; FEEDLOT CATTLE; ANTIGENIC CHARACTERIZATION; GNOTOBIOTIC CALVES; IMMUNE-RESPONSE; WEIGHT-GAIN; VSP LOCUS;
D O I
10.1016/j.vetmic.2015.02.024
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bovine mycoplasmosis due to Mycoplasma bovis causes several important bovine diseases such as pneumonia, mastitis, arthritis, otitis, genital disorders or keratoconjunctivitis. Variable surface lipoproteins, adhesion, invasion of host cells, modulation of the host immune system, biofilm formation and the release of secondary metabolites like hydrogen peroxide, as well as synergistic infections with other bacterial or viral pathogens are among the more significantly studied characteristics of the bacterium. The aim of this review is to summarize the current knowledge regarding the virulence of M. bovis and additionally, factors contributing to the dissemination and persistence of this pathogen in the bovine host will be discussed. (C) 2015 The Authors. Published by Elsevier B.V.
引用
收藏
页码:15 / 22
页数:8
相关论文
共 74 条
[1]   IMMUNOHISTOCHEMICAL AND PATHOLOGICAL-STUDY OF MYCOPLASMA BOVIS-ASSOCIATED LUNG ABSCESSES IN CALVES [J].
ADEGBOYE, DS ;
HALBUR, PG ;
CAVANAUGH, DL ;
WERDIN, RE ;
CHASE, CCL ;
MISKIMINS, DW ;
ROSENBUSCH, RF .
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 1995, 7 (03) :333-337
[2]   Molecular and antigenic characterization of a Mycoplasma bovis strain causing an outbreak of infectious keratoconjunctivitis [J].
Alberti, A ;
Addis, MF ;
Chessa, B ;
Cubeddu, T ;
Profiti, M ;
Rosati, S ;
Ruiu, A ;
Pittau, M .
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 2006, 18 (01) :41-51
[3]   Mycoplasma bovis isolated from brain tissue of calves [J].
Ayling, R ;
Nicholas, R ;
Hogg, R ;
Wessels, J ;
Scholes, S ;
Byrne, W ;
Hill, M ;
Moriarty, J ;
O'Brien, T .
VETERINARY RECORD, 2005, 156 (12) :391-392
[4]   A FAMILY OF PHASE-VARIANT AND SIZE-VARIANT MEMBRANE-SURFACE LIPOPROTEIN ANTIGENS (VSPS) OF MYCOPLASMA-BOVIS [J].
BEHRENS, A ;
HELLER, M ;
KIRCHHOFF, H ;
YOGEV, D ;
ROSENGARTEN, R .
INFECTION AND IMMUNITY, 1994, 62 (11) :5075-5084
[5]   Immunoelectron microscopic localization of variable proteins on the surface of Mycoplasma bovis [J].
Behrens, A ;
Heller, M ;
Rosenbusch, R ;
Kirchhoff, H .
MICROBIOLOGY-UK, 1996, 142 :1863-1871
[6]   Intraspecies polymorphism of vsp genes and expression profiles of variable surface protein antigens (Vsps) in field isolates of Mycoplasma bovis [J].
Beier, T ;
Hotzel, H ;
Lysnyansky, I ;
Grajetzki, C ;
Heller, M ;
Rabeling, B ;
Yogev, D ;
Sachse, K .
VETERINARY MICROBIOLOGY, 1998, 63 (2-4) :189-203
[7]  
Booker CW, 2008, CAN VET J, V49, P473
[8]  
Booker CW, 1999, CAN VET J, V40, P40
[9]   Expression of Mycoplasma bovis variable surface membrane proteins in the respiratory tract of calves after experimental infection with a clonal variant of Mycoplasma bovis type strain PG45 [J].
Buchenau, I. ;
Poumarat, F. ;
Le Grand, D. ;
Linkner, H. ;
Rosengarten, R. ;
Hewicker-Trautwein, M. .
RESEARCH IN VETERINARY SCIENCE, 2010, 89 (02) :223-229
[10]   Characterization of the immune response to Mycoplasma bovis lung infection [J].
Bush, TJV ;
Rosenbusch, RF .
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2003, 94 (1-2) :23-33