Non-invasive Brain Stimulation, a Tool to Revert Maladaptive Plasticity in Neuropathic Pain

被引:34
|
作者
Naro, Antonino [1 ]
Milardi, Demetrio [1 ,2 ]
Russo, Margherita [1 ]
Terranova, Carmen [3 ]
Rizzo, Vincenzo [3 ]
Cacciola, Alberto [1 ,2 ]
Marino, Silvia [1 ]
Calabro, Rocco S. [1 ]
Quartarone, Angelo [1 ,2 ]
机构
[1] IRCCS Ctr Neurolesi Bonino Pulejo, Messina, Italy
[2] Univ Messina, Dept Biomed Dental Sci & Morphol & Funct Images, Messina, Italy
[3] Univ Messina, Dept Clin & Expt Med, Messina, Italy
来源
关键词
TMS; neuropathic pain; NIBS; plasticity; tDCS; TRANSCRANIAL MAGNETIC STIMULATION; HUMAN MOTOR CORTEX; CEREBRAL-BLOOD-FLOW; PERIPHERAL-NERVE INJURY; SPINAL-CORD-INJURY; DORSOLATERAL PREFRONTAL CORTEX; ROSTRAL VENTROMEDIAL MEDULLA; FOCAL HAND DYSTONIA; OF-THE-ART; CENTRAL SENSITIZATION;
D O I
10.3389/fnhum.2016.00376
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Neuromodulatory effects of non-invasive brain stimulation (NIBS) have been extensively studied in chronic pain. A hypothetic mechanism of action would be to prevent or revert the ongoing maladaptive plasticity within the pain matrix. In this review, the authors discuss the mechanisms underlying the development of maladaptive plasticity in patients with chronic pain and the putative mechanisms of NIBS in modulating synaptic plasticity in neuropathic pain conditions.
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页数:9
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