Sequential three-component reaction of homophthalonitrile, salicylaldehydes and nitromethane

被引:14
作者
Festa, Alexey A. [1 ]
Storozhenko, Olga A. [1 ]
Ndoutoume, Delphine R. Bella [1 ]
Varlamov, Alexey V. [1 ]
Voskressensky, Leonid G. [1 ]
机构
[1] RUDN Univ, Dept Organ Chem, Moscow 117198, Russia
基金
俄罗斯基础研究基金会;
关键词
AGENTS; POT;
D O I
10.1016/j.mencom.2017.09.006
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An effective preparative multi-component synthesis of 12-nitromethyl-12H-chromeno[2,3-c]isoquinolin-5-amines comprised sequential reactions of salicylaldehydes with homophthalonitrite and then with nitromethane under MW irradiation.
引用
收藏
页码:451 / 453
页数:3
相关论文
共 11 条
  • [1] Topical pranoprofen 0.1% is as effective anti-inflammatory and analgesic agent as diclofenac sodium 0.1% after strabismus surgery
    Akyol-Salman, Ilknur
    Lece-Sertoz, Deniz
    Baykal, Orhan
    [J]. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2007, 23 (03) : 280 - 283
  • [2] Discovery of 4-Aryl-4H-Chromenes as Potent Apoptosis Inducers Using a Cell- and Caspase-Based Anti-Cancer Screening Apoptosis Program (ASAP): SAR Studies and the Identification of Novel Vascular Disrupting Agents
    Cai, Sui Xiong
    Drewe, John
    Kemnitzer, William
    [J]. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2009, 9 (04) : 437 - 456
  • [3] Solvent-free cascade reaction: direct multicomponent assembling of 2-amino-4H-chromene scaffold from salicylaldehyde, malononitrile or cyanoacetate and nitroalkanes
    Elinson, Michail N.
    Ilovaisky, Alexey I.
    Merkulova, Valentina M.
    Belyakov, Pavel A.
    Chizhov, Alexander O.
    Nikishin, Gennady I.
    [J]. TETRAHEDRON, 2010, 66 (23) : 4043 - 4048
  • [4] Toxicological and pharmacological evaluation, antioxidant, ADMET and molecular modeling of selected racemic chromenotacrines {11-amino-12-aryl-8,9,10,12-tetrahydro-7H-chromeno[2,3-b]quinolin-3-ols} for the potential prevention and treatment of Alzheimer's disease
    Jesus Oset-Gasque, Maria
    Pilar Gonzalez, Maria
    Perez-Pena, Javier
    Garcia-Font, Nuria
    Romero, Alejandro
    del Pino, Javier
    Ramos, Eva
    Hadjipavlou-Litina, Dimitra
    Soriano, Elena
    Chioua, Mourad
    Samadi, Abdelouahid
    Raghuvanshi, Dushyant S.
    Singh, Krishna N.
    Marco-Contelles, Jose
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 74 : 491 - 501
  • [5] Synthesis and Characterization of Novel 2-Amino-Chromene-Nitriles that Target Bcl-2 in Acute Myeloid Leukemia Cell Lines
    Keerthy, Hosadurga K.
    Garg, Manoj
    Mohan, Chakrabhavi D.
    Madan, Vikas
    Kanojia, Deepika
    Shobith, Rangappa
    Nanjundaswamy, Shivananju
    Mason, Daniel J.
    Bender, Andreas
    Basappa
    Rangappa, Kanchugarakoppal S.
    Koeffler, Phillip
    [J]. PLOS ONE, 2014, 9 (09):
  • [6] Antimycobacterial activity of novel 1,2,4-oxadiazole-pyranopyridine/chromene hybrids generated by chemoselective 1,3-dipolar cycloadditions of nitrile oxides
    Kumar, Raju Ranjith
    Perumal, Subbu
    Carlos Menendez, J.
    Yogeeswari, Perumal
    Sriram, Dharmarajan
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (11) : 3444 - 3450
  • [7] A Pd-mediated new strategy to functionalized 2-aminochromenes: Their in vitro evaluation as potential anti tuberculosis agents
    Reddy, T. Ram
    Reddy, L. Srinivasula
    Reddy, G. Rajeshwar
    Nuthalapati, Venkata Subbaiah
    Lingappa, Y.
    Sandra, Sandhya
    Kapavarapu, Ravikumar
    Misra, Parimal
    Pal, Manojit
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 21 (21) : 6433 - 6439
  • [8] PbS nanoparticles stabilized on HPG-modified FeNi3 as catalyst for synthesis of 2-amino-4H-chromene under mild conditions
    Sadeghzadeh, Seyed Mohsen
    Nasseri, Mohammad Ali
    [J]. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2014, 11 (04) : 1197 - 1205
  • [9] Pot, atom and step economic (PASE) synthesis of 5-isoxazolyl-5H-chromeno[2,3-b]pyridine scaffold
    Vereshchagin, Anatoly N.
    Elinson, Michail N.
    Anisina, Yuliya E.
    Ryzhkov, Fedor V.
    Goloveshkin, Alexander S.
    Bushmarinov, Ivan S.
    Zlotin, Sergey G.
    Egorov, Mikhail P.
    [J]. MENDELEEV COMMUNICATIONS, 2015, 25 (06) : 424 - 426
  • [10] Experimental and Theoretical Investigation of One-pot Synthesis of 2-Amino-4H-chromenes Catalyzed by Basic-functionalized Ionic Liquids
    Wang Yuanyuan
    Wu Yuetong
    Wang Yu
    Dai Liyi
    [J]. CHINESE JOURNAL OF CHEMISTRY, 2012, 30 (08) : 1709 - 1714