Executive functions in autism and Asperger's disorder: Flexibility, fluency, and inhibition

被引:126
作者
Kleinhans, N
Akshoomoff, N
Delis, DC
机构
[1] San Diego State Univ, Joint Doctoral Program Clin Psychol, La Jolla, CA 92037 USA
[2] Univ Calif San Diego, Dept Psychiat, Sch Med, San Diego, CA 92103 USA
[3] Childrens Hosp, Child & Adolescent Serv Res Ctr, San Diego, CA USA
关键词
D O I
10.1207/s15326942dn2703_5
中图分类号
B844 [发展心理学(人类心理学)];
学科分类号
040202 ;
摘要
The Color-Word Interference Test, Trail Making Test, Verbal Fluency Test, and Design Fluency Test from the Delis-Kaplan Executive Function System (Delis, Kaplan, & Kramer, 2001) were administered to 12 high-functioning adults and adolescents with autistic disorder or Asperger's disorder. Each test included a switching condition in addition to baseline and/or other executive-function conditions. Participants performed significantly below average on a composite measure of executive functioning adjusted for baseline cognitive ability. Complex verbal tasks that required cognitive switching and initiation of efficient lexical retrieval strategies produced the most consistent deficits, whereas cognitive inhibition was intact. We discuss implications of these findings for understanding the neurocognitive substrates of autistic spectrum disorders.
引用
收藏
页码:379 / 401
页数:23
相关论文
共 64 条
[1]   The neurobiological basis of autism from a developmental perspective [J].
Akshoomoff, N ;
Pierce, K ;
Courchesne, E .
DEVELOPMENT AND PSYCHOPATHOLOGY, 2002, 14 (03) :613-634
[2]   Attention coordination and anticipatory control [J].
Akshoomoff, NA ;
Courchesne, E ;
Townsend, J .
CEREBELLUM AND COGNITION, 1997, 41 :575-598
[3]   Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: An fMRI study of autism [J].
Allen, G ;
Courchesne, E .
AMERICAN JOURNAL OF PSYCHIATRY, 2003, 160 (02) :262-273
[4]  
Army Individual Test Battery, 1944, MAN DIR SCOR
[5]  
Belmonte M., 2000, Autism, V4, P269, DOI DOI 10.1177/1362361300004003004
[6]  
Bennetto L, 1996, CHILD DEV, V67, P1816, DOI 10.1111/j.1467-8624.1996.tb01830.x
[7]   A SIMPLE OBJECTIVE TECHNIQUE FOR MEASURING FLEXIBILITY IN THINKING [J].
Berg, Esta A. .
JOURNAL OF GENERAL PSYCHOLOGY, 1948, 39 (01) :15-22
[8]   TOWER OF HANOI PERFORMANCE OF RETARDED YOUNG-ADULTS AND NONRETARDED-CHILDREN AS A FUNCTION OF SOLUTION LENGTH AND GOAL STATE [J].
BORYS, SV ;
SPITZ, HH ;
DORANS, BA .
JOURNAL OF EXPERIMENTAL CHILD PSYCHOLOGY, 1982, 33 (01) :87-110
[9]   WORD FLUENCY IN HIGH-FUNCTIONING AUTISTIC-CHILDREN [J].
BOUCHER, J .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 1988, 18 (04) :637-645
[10]   Inhibitory mechanisms in autism spectrum disorders: typical selective inhibition of location versus facilitated perceptual processing [J].
Brian, JA ;
Tipper, SP ;
Weaver, B ;
Bryson, SE .
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 2003, 44 (04) :552-560