Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery

被引:53
作者
Chang, Yincheng [1 ]
Hou, Chenxi [1 ]
Ren, Jingli [1 ]
Xin, Xiaoting [1 ]
Pei, Yuxin [1 ]
Lu, Yuchao [1 ]
Cao, Shoupeng [1 ]
Pei, Zhichao [1 ]
机构
[1] Northwest A&F Univ, Shaanxi Key Lab Nat Prod & Chem Biol, Coll Sci, Yangling 712100, Shaanxi, Peoples R China
基金
中国国家自然科学基金;
关键词
ANTICANCER DRUG; WATER; RELEASE; RECOGNITION; NANOPARTICLES; SYSTEM; VIVO;
D O I
10.1039/c6cc03637f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Supramolecular vesicles based on the host-guest complexation of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative have been constructed, which showed dual-responsiveness and cancer cells targetability resulting from its ferrocenecarboxylic acid units and galactose units, respectively. This work provides a good example for the construction of multifunctional nanocarriers for targeted drug delivery.
引用
收藏
页码:9578 / 9581
页数:4
相关论文
共 35 条
[1]   Lipid-Peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo [J].
Al-Ahmady, Zahraa S. ;
Al-Jamal, Wafa' T. ;
Bossche, Jeroen V. ;
Bui, Tam T. ;
Drake, Alex F. ;
Mason, A. James ;
Kostarelos, Kostas .
ACS NANO, 2012, 6 (10) :9335-9346
[2]   Delivery of Nucleic Acids via Disulfide-Based Carrier Systems [J].
Bauhuber, Sonja ;
Hozsa, Constantin ;
Breunig, Miriam ;
Goepferich, Achim .
ADVANCED MATERIALS, 2009, 21 (32-33) :3286-3306
[3]   Multistimuli-Responsive Supramolecular Vesicles Based on Water-Soluble Pillar[6]arene and SAINT Complexation for Controllable Drug Release [J].
Cao, Yu ;
Hu, Xiao-Yu ;
Li, Yan ;
Zou, Xiaochun ;
Xiong, Shuhan ;
Lin, Chen ;
Shen, Ying-Zhong ;
Wang, Leyong .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (30) :10762-10769
[4]   Cationic Vesicles Based on Amphiphilic Pillar[5]arene Capped with Ferrocenium: A Redox-Responsive System for Drug/siRNA Co-Delivery [J].
Chang, Yincheng ;
Yang, Kui ;
Wei, Peng ;
Huang, Sisi ;
Pei, Yuxin ;
Zhao, Wei ;
Pei, Zhichao .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (48) :13126-13130
[5]   Chiral Selective Transmembrane Transport of Amino Acids through Artificial Channels [J].
Chen, Lei ;
Si, Wen ;
Zhang, Liang ;
Tang, Gangfeng ;
Li, Zhan-Ting ;
Hou, Jun-Li .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (06) :2152-2155
[6]   A Dual-Thermoresponsive Gemini-Type Supra-amphiphilic Macromolecular [3]Pseudorotaxane Based on Pillar[10]arene/Paraquat Cooperative Complexation [J].
Chi, Xiaodong ;
Yu, Guocan ;
Shao, Li ;
Chen, Jianzhuang ;
Huang, Feihe .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (09) :3168-3174
[7]   A Dual-Responsive Supra-Amphiphilic Polypseudorotaxane Constructed from a Water-Soluble Pillar[7]arene and an Azobenzene-Containing Random Copolymer [J].
Chi, Xiaodong ;
Ji, Xiaofan ;
Xia, Danyu ;
Huang, Feihe .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 137 (04) :1440-1443
[8]   pH-Responsive Supramolecular Vesicles Based on Water-Soluble Pillar[6]arene and Ferrocene Derivative for Drug Delivery [J].
Duan, Qunpeng ;
Cao, Yu ;
Li, Yan ;
Hu, Xiaoyu ;
Xiao, Tangxin ;
Lin, Chen ;
Pan, Yi ;
Wang, Leyong .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (28) :10542-10549
[9]   Enzyme-responsive pillar[5]arene-based polymer-substituted amphiphiles: synthesis, self-assembly in water, and application in controlled drug release [J].
Gao, Lingyan ;
Zheng, Bo ;
Chen, Wei ;
Schalley, Christoph A. .
CHEMICAL COMMUNICATIONS, 2015, 51 (80) :14901-14904
[10]   DNAzyme-based biosensors and nanodevices [J].
Gong, Liang ;
Zhao, Zilong ;
Lv, Yi-Fan ;
Huan, Shuang-Yan ;
Fu, Ting ;
Zhang, Xiao-Bing ;
Shen, Guo-Li ;
Yu, Ru-Qin .
CHEMICAL COMMUNICATIONS, 2015, 51 (06) :979-995