Enantiodivergent, catalytic asymmetric synthesis of γ-amino vinyl sulfones

被引：17

作者：

Picó, A ^{[1
]}

Moyano, A ^{[1
]}

Pericàas, MA ^{[1
]}

机构：

[1] Univ Barcelona, Fac Quim, Dept Quim Organ, Unit Recerca Sintesi Asimetrica, Barcelona 08028, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 13期

关键词：

D O I：

10.1021/jo0268456

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A set of diversely substituted N-Boc-gamma-amino vinyl sulfones has been prepared by a four-step procedure from readily available, highly enantiopure anti-N-Boc-3-amino-1,2-alkanediols. This new route, which does not depend on the accessibility of alpha-amino acids as starting materials, is noteworthy for its efficiency, for its generality, and for the fact that both enantiomers of a given gamma-amino vinyl sulfone can be obtained with equal ease.

引用

页码：5075 / 5083

页数：9

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