Effects of the carbonate content in carbonate apatite on bone replacement

被引:17
作者
Deguchi, Kaai [1 ,2 ]
Nomura, Shunsuke [1 ]
Tsuchiya, Akira [2 ]
Takahashi, Ichiro [1 ]
Ishikawa, Kunio [2 ]
机构
[1] Kyushu Univ, Fac Dent Sci, Div Oral Hlth Growth & Dev, Sect Orthodont, Fukuoka, Japan
[2] Kyushu Univ, Fac Dent Sci, Dept Biomat, Fukuoka, Japan
关键词
carbonate apatite; carbonate content; osteoclastic resorption; resorbability; ALPHA-TRICALCIUM PHOSPHATE; DISSOLUTION-PRECIPITATION REACTION; SETTING REACTION; FABRICATION; HYDROXYAPATITE; FOAM; OSTEOCLAST; CRYSTALLINITY; GRANULES; BLOCKS;
D O I
10.1002/term.3270
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Carbonate apatite (CO(3)Ap), an inorganic component of human bone, has been clinically applied as an artificial bone substitute. In this study, the effects of the CO3 content in CO(3)Ap on the replacement by new bone were studied by fabricating CO(3)Ap granules containing 0.9-8.3 wt% of CO3. The dissolution rate of CO(3)Ap in a weak acidic solution, mimicking the Howship's lacunae, was rapid for the CO(3)Ap granules containing a larger amount of CO3. Histological analyses demonstrated the rapid resorption in CO(3)Ap and replacement by natural bone tissue when the CO3 content was increased. Therefore, the CO3 content in CO(3)Ap is a key factor that influences the replacement of the bone tissue.
引用
收藏
页码:200 / 206
页数:7
相关论文
共 34 条
[1]  
[Anonymous], 2012, T03303 JIS
[2]   Fabrication of interconnected porous calcium-deficient hydroxyapatite using the setting reaction of a tricalcium phosphate spherical granules [J].
Arifta, Tya Indah ;
Munar, Melvin L. ;
Tsuru, Kanji ;
Ishikawa, Kunio .
CERAMICS INTERNATIONAL, 2017, 43 (14) :11149-11155
[3]   Histological Comparison in Rats between Carbonate Apatite Fabricated from Gypsum and Sintered Hydroxyapatite on Bone Remodeling [J].
Ayukawa, Yasunori ;
Suzuki, Yumiko ;
Tsuru, Kanji ;
Koyano, Kiyoshi ;
Ishikawa, Kunio .
BIOMED RESEARCH INTERNATIONAL, 2015, 2015
[4]   The Great Beauty of the osteoclast [J].
Cappariello, Alfredo ;
Maurizi, Antonio ;
Veeriah, Vimal ;
Teti, Anna .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2014, 558 :70-78
[5]   Osteoclasts: more than 'bone eaters' [J].
Charles, Julia F. ;
Aliprantis, Antonios O. .
TRENDS IN MOLECULAR MEDICINE, 2014, 20 (08) :449-459
[6]   Fabrication of carbonate apatite block based on internal dissolution-precipitation reaction of dicalcium phosphate and calcium carbonate [J].
Daitou, Fumikazu ;
Maruta, Michito ;
Kawachi, Giichiro ;
Tsuru, Kanji ;
Matsuya, Shigeki ;
Terada, Yoshihiro ;
Ishikawa, Kunio .
DENTAL MATERIALS JOURNAL, 2010, 29 (03) :303-308
[7]   Honeycomb blocks composed of carbonate apatite, β-tricalcium phosphate, and hydroxyapatite for bone regeneration: effects of composition on biological responses [J].
Hayashi, K. ;
Kishida, R. ;
Tsuchiya, A. ;
Ishikawa, K. .
MATERIALS TODAY BIO, 2019, 4
[8]  
Ishikawa, 2016, HDB BIOCERAMICS BIOC, P213, DOI DOI 10.1007/978-3-319-12460-5_8
[9]   Carbonate apatite bone replacement: learn from the bone [J].
Ishikawa, Kunio .
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 2019, 127 (09) :595-601
[10]  
Ishikawa K, 2017, HANDBOOK OF INTELLIGENT SCAFFOLDS FOR TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2ND EDITION, P141