A non-random gait through the human genome

被引:0
作者
Huang, Moli [1 ]
Zhu, Huangqiong [1 ]
Shen, Bairong [1 ,2 ,3 ]
Gao, Ge [4 ]
机构
[1] Soochow Univ, Ctr Syst Biol, Suzhou 215006, Peoples R China
[2] Tongji Univ, Dept Biomed Engn, Shanghai 200092, Peoples R China
[3] Univ Tampere, Inst Med Technol, Tampere FIN-33014, Finland
[4] Peking Univ, Ctr Bioinformat, Natl Lab Protein Engn & Plant Genet Engn, Beijing, Peoples R China
来源
2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11 | 2009年
关键词
intergenic distance; normal distribution; stationary value; GENE-CLUSTER;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
With the accumulation of genomic data, it is increasingly clear that eukaryotic genes do not randomly distribute in chromosomes. In this study, we investigated the distribution of 27142 genes mapped at whole chromosomes reported in the Human Genome Data Base as of January 2007. We provide first evidence that distances of neighbour genes follow normal distribution after data transformation. Moreover, our studies first reveal that intergenic distances on every chromosome are convergent to one stationary value.
引用
收藏
页码:884 / +
页数:2
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