Repurposing Tecfidera for cancer

被引：7
作者：
Booth, Laurence
Malkin, Mark
Dent, Paul [1 ,2 ,3 ]
机构：
[1] Virginia Commonwealth Univ, Sch Med, Dept Biochem, Richmond, VA 23298 USA
[2] Virginia Commonwealth Univ, Sch Med, Dept Mol Biol, Richmond, VA 23298 USA
[3] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA 23298 USA
来源：
AGING-US | 2016年 / 8卷 / 07期
关键词：
dimethyl fumarate (DMF); monomethyl fumarate (MMF); Tecfidera; ruxolitinib; Jakafi; glioblastoma multiforme; oncology; INHIBITORS; CELLS; KILL;
D O I：
10.18632/aging.101001
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：1289 / 1290
页数：2
相关论文
共 7 条
[1]   Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo [J].
Booth, Laurence ;
Albers, Thomas ;
Roberts, Jane L. ;
Tavallai, Mehrad ;
Poklepovic, Andrew ;
Lebedyeva, Iryna O. ;
Dent, Paul .
ONCOTARGET, 2016, 7 (26) :40398-40417
[2]   PDE5 Inhibitors Enhance Celecoxib Killing in Multiple Tumor Types [J].
Booth, Laurence ;
Roberts, Jane L. ;
Cruickshanks, Nichola ;
Tavallai, Seyedmehrad ;
Webb, Timothy ;
Samuel, Peter ;
Conley, Adam ;
Binion, Brittany ;
Young, Harold F. ;
Poklepovic, Andrew ;
Spiegel, Sarah ;
Dent, Paul .
JOURNAL OF CELLULAR PHYSIOLOGY, 2015, 230 (05) :1115-1127
[3]   Regulation of dimethyl-fumarate toxicity by proteasome inhibitors [J].
Booth, Laurence ;
Cruickshanks, Nichola ;
Tavallai, Seyedmehrad ;
Roberts, Jane L. ;
Peery, Matthew ;
Poklepovic, Andrew ;
Dent, Paul .
CANCER BIOLOGY & THERAPY, 2014, 15 (12) :1646-1657
[4]   Rationally Repurposing Ruxolitinib (Jakafi®) as a Solid Tumor Therapeutic [J].
Tavallai, Mehrad ;
Booth, Laurence ;
Roberts, Jane L. ;
Poklepovic, Andrew ;
Dent, Paul .
FRONTIERS IN ONCOLOGY, 2016, 6
[5]   Ruxolitinib synergizes with DMF to kill via BIM plus BAD-induced mitochondrial dysfunction and via reduced SOD2/TRX expression and ROS [J].
Tavallai, Mehrad ;
Booth, Laurence ;
Roberts, Jane L. ;
McGuire, William P. ;
Poklepovic, Andrew ;
Dent, Paul .
ONCOTARGET, 2016, 7 (14) :17290-17300
[6]   Nexavar/Stivarga and Viagra Interact to Kill Tumor Cells [J].
Tavallai, Mehrad ;
Hamed, Hossein A. ;
Roberts, Jane L. ;
Cruickshanks, Nichola ;
Chuckalovcak, John ;
Poklepovic, Andrew ;
Booth, Laurence ;
Dent, Paul .
JOURNAL OF CELLULAR PHYSIOLOGY, 2015, 230 (09) :2281-2298
[7]   Celecoxib enhances [sorafenib plus sildenafil] lethality in cancer cells and reverts platinum chemotherapy resistance [J].
Webb, Timothy ;
Carter, Jori ;
Roberts, Jane L. ;
Poklepovic, Andrew ;
McGuire, William P. ;
Booth, Laurence ;
Dent, Paul .
CANCER BIOLOGY & THERAPY, 2015, 16 (11) :1660-1670
1