Does active learning through an antisense jigsaw make sense?

被引:5
作者
Seetharaman, M
Musier-Forsyth, K
机构
[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Med Chem, Minneapolis, MN 55455 USA
关键词
D O I
10.1021/ed080p1404
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:1404 / 1407
页数:4
相关论文
共 11 条
[1]   Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides [J].
Agrawal, S .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1999, 1489 (01) :53-68
[2]  
Aronson E., 1997, JIGSAW CLASSROOM BUI
[3]  
Bloom B. S., 1956, HDB 1 COGNITIVE DOMA
[4]   Binding studies with mutants of Zif268 - Contribution of individual side chains to binding affinity and specificity in the Zif268 zinc finger-DNA complex [J].
Elrod-Erickson, M ;
Pabo, CO .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (27) :19281-19285
[5]   A general strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites [J].
Greisman, HA ;
Pabo, CO .
SCIENCE, 1997, 275 (5300) :657-661
[6]   Oligonucleotide N3′ → P5′ phosphoramidates as potential therapeutic agents [J].
Gryaznov, SM .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1999, 1489 (01) :131-140
[7]   2′-Carbohydrate modifications in antisense oligonucleotide therapy:: importance of conformation, configuration and conjugation [J].
Manoharan, M .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1999, 1489 (01) :117-130
[8]   The structural basis of hammerhead ribozyme self-cleavage [J].
Murray, JB ;
Terwey, DP ;
Maloney, L ;
Karpeisky, A ;
Usman, N ;
Beigelman, L ;
Scott, WG .
CELL, 1998, 92 (05) :665-673
[9]   Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations [J].
O'Rear, JL ;
Wang, SL ;
Feig, AL ;
Beigelman, L ;
Uhlenbeck, OC ;
Herschlag, D .
RNA, 2001, 7 (04) :537-545
[10]   Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases [J].
Peracchi, A ;
Beigelman, L ;
Usman, N ;
Herschlag, D .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (21) :11522-11527