Delayed feedback control of synchronization in locally coupled neuronal networks

被引:46
作者
Hauptmann, C [1 ]
Popovych, O
Tass, PA
机构
[1] Res Ctr Juelich, Inst Med, D-52425 Julich, Germany
[2] Res Ctr Juelich, Virtual Inst Neuromodulat, D-52425 Julich, Germany
[3] Univ Hosp, Dept Stereotax & Funct Neurosurg, D-50924 Cologne, Germany
关键词
parkinsonian disease; deep brain stimulation; delayed feedback; microscopic modeling;
D O I
10.1016/j.neucom.2004.10.072
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
We present a novel, particularly robust technique for effective desynchronization of neuronal populations in the presence of noise. Delayed feedback signals are administered in a spatially coordinated way via four stimulation sites using different delays for each stimulation site, respectively. The technique is numerically tested in a phase oscillator model and in a physiologically realistic model. We propose our methods as novel, particularly mild and effective stimulation protocols for the therapy of patients suffering from Parkinson's disease, essential tremor or epilepsy. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:759 / 767
页数:9
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